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UnknownGametophytic selection in Arabidopsis thaliana supports the selective model of intron length reduction.
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S-EPMC1186733 | biostudies-literature
TranscriptomicsA mutation in a splicing factor that causes retinitis pigmentosa (RP) has a transcriptome-wide effect on mRNA splicing
Background: Substantial progress has been made in the identification of sequence elements that control mRNA splicing and the genetic variants in these elements that alter mRNA splicing (referred to as splicing quantitative trait loci -- sQTLs). Genetic variants that affect mRNA splicing in trans are...
ORGANISM(S): Homo sapiens 
2012-12-25 | E-GEOD-43134 | biostudies-arrayexpress
TranscriptomicsThe miRNAome of the postpartum dairy cow liver in negative energy balance
Negative energy balance (NEB) is an altered metabolic state in high yielding cows that occurs during the first few weeks postpartum when energy demands for lactation and maintenance exceed the energy supply from dietary intake. NEB can, in turn, lead to metabolic disorders and to reduced fertility. ...
ORGANISM(S): Bos taurus 
2014-03-14 | E-GEOD-55882 | biostudies-arrayexpress
TranscriptomicsmiRNA expression data from post-partum dairy cattle (Holstein Friesian) liver
High yielding dairy cattle undergo a state of NEB (negative energy balance) during the post-partum period when energy demand for lactation and maintenance exceeds energy intake. During this period in order to counteract NEB the liver under goes extensive metabolic and physiological change resulting ...
ORGANISM(S): Bos taurus 
2013-10-25 | E-GEOD-51658 | biostudies-arrayexpress
TranscriptomicsBias in Gene-Set Analysis Applied to High-throughput Methylation Data
Gene set analysis as it is typically applied to genome-wide methylation assays is severely biased as a result of differences in the numbers and sizes of CpG islands associated with different classes of genes. We demonstrate this bias using published data from a study of differential methylation in l...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39188 | biostudies-arrayexpress
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