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ProteomicsIdentification of Biomarkers and Therapeutic Targets Related to Sepsis-associated Encephalopathy in Rats by Quantitative Proteomics
Background: Sepsis-associated encephalopathy (SAE) is a common and severe complication of sepsis. While several studies have reported the proteomic alteration in plasma, urine, heart, etc. of sepsis, few research focused on the brain tissue. This study aims at discovering the differentially abundant...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-03-10 | PXD035112 | Pride
Quantitative proteomics Pi3k/akt signaling Acute phase response Sepsis-associated encephalopathy Gc 
GenomicsBrain Genexpession of a mouse modle of Sepsis-associated encephalopathy (SAE)
Brain Genexpession of a mouse modle of Sepsis-associated encephalopathy (SAE)
PRJNA705148 | ENA
Genomics
sepsis-associated encephalopathy
PRJNA827799 | ENA
UnknownSepsis-Associated Encephalopathy: From Delirium to Dementia?
Not available
S-EPMC7141293 | biostudies-literature
TranscriptomicsBrain Genexpession of a mouse modle of Sepsis-associated encephalopathy (SAE)
Sepsis-associated encephalopathy (SAE) is a major and frequent complication in patients with sepsis resulting in delirium and premature death. Sepsis survivors commonly suffer from long-term cognitive impairment causing immense burden on patients, caregivers, and economic health systems. Underlying ...
ORGANISM(S): Mus musculus 
2021-02-27 | GSE167610 | GEO
GenomicsN-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABABR1 mRNA in sepsis-associated encephalopathy.
N-acetyltransferase 10 mediates cognitive dysfunction through the acetylation of GABABR1 mRNA in sepsis-associated encephalopathy.
PRJNA1065257 | ENA
UnknownIntraperitoneal hypertension, a novel risk factor for sepsis-associated encephalopathy in sepsis mice.
Not available
S-EPMC5970176 | biostudies-literature
GenomicsHexokinase 2 Exacerbates Mitochondrial Damage, Neuroinflammation, and Lipid accumulation by promoting ACSL4 ISGylation in Sepsis-Associated Encephalopathy
Hexokinase 2 Exacerbates Mitochondrial Damage, Neuroinflammation, and Lipid accumulation by promoting ACSL4 ISGylation in Sepsis-Associated Encephalopathy
PRJNA1180095 | ENA
Genomics
Gut microbiota diversity in a mice model of Sepsis Associated Encephalopathy
PRJNA767832 | ENA
GenomicsCuscuta chinensis Lam. Flavonoids (CCLF) alleviate the symptoms of sepsis-associated encephalopathy via PI3K/AKT/Nrf2/HO-1 pathway
Cuscuta chinensis Lam. Flavonoids (CCLF) alleviate the symptoms of sepsis-associated encephalopathy via PI3K/AKT/Nrf2/HO-1 pathway
PRJNA1049778 | ENA
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