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GenomicsHuman serpina3 modulates cortex expansion and folding
Human serpina3 modulates cortex expansion and folding
PRJNA694137 | ENA
GenomicsRNA-seq of chondrogenesis following siRNA depletion of SERPINA3
RNA-seq of chondrogenesis following siRNA depletion of SERPINA3
PRJNA1038778 | ENA
GenomicsRNA-seq of osteogenesis following siRNA depletion of SERPINA3
RNA-seq of osteogenesis following siRNA depletion of SERPINA3
PRJNA1039295 | ENA
GenomicsSerpina3 modulates neuronal cell fate determination (scRNA sequencing)
Serpina3 modulates neuronal cell fate determination (scRNA sequencing)
PRJNA694621 | ENA
TranscriptomicsSERPINA3- a novel keratinocyte differentiation promotor mediates epidermal barrier repair response in psoriatic lesion
To excavate the genes regulated by SERPINA3, We profiled SERPINA3 silenced differentiated KC versus control using a RNA-seq approach. The genes down regulated in SERPINA3 silenced cells represent targets that are positively regulated by SERPINA3.
ORGANISM(S): Homo sapiens 
2017-07-29 | GSE102000 | GEO
TranscriptomicsHuman serpina3 modulates cortex expansion and folding
Purpose:To gain a deeper insight into how Serpina3 regulates neurogenesis and further controling cortex folding in mice brain, RNA-sequencing (RNA-seq) was performed to analyze the genome-wide changes by TCF20 deletion at E15. Methods: Total RNA was extracted from E15 telencephalic tissue of WT and ...
ORGANISM(S): Mus musculus 
2021-01-23 | GSE165345 | GEO
ProteomicsCSF SERPINA3 levels are increased in patients with progressive multiple sclerosis
One of the most challenging aspects in multiple sclerosis (MS) research is to understand the mechanisms leading to neurodegeneration and subsequent tissue repair. Here, we aimed to identify biomarkers associated with the progressive phases of the disease that may have neuroprotective potential. To a...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-01 | PXD018173 | Pride
Proteomics Multiple sclerosis 
TranscriptomicsRNA-seq of osteogenesis following siRNA depletion of SERPINA3
SERPINA3 knockdown was observed to reduce cartilage pellet size following differentiation of mesenchymal stem cells (MSCs) to chondrocytes. To additionally understand any effects on the osteogenesis transcriptome, RNA-sequencing was conducted on primary MSCs depleted of SERPINA3 with siRNA and compa...
ORGANISM(S): Homo sapiens 
2024-08-05 | GSE247528 | GEO
TranscriptomicsRNA-seq of chondrogenesis following siRNA depletion of SERPINA3
SERPINA3 knockdown was observed to reduce cartilage pellet size following differentiation of mesenchymal stem cells (MSCs) to chondrocytes. To understand the global effects on the chondrocyte transcriptome, RNA-sequencing was conducted on primary MSCs depleted of SERPINA3 with siRNA and compared to ...
ORGANISM(S): Homo sapiens 
2024-08-05 | GSE247491 | GEO
TranscriptomicsSerpina3 modulates neuronal cell fate determination (scRNA sequencing)
Purpose: To better understand how Serpina3 modulate cortex enpansion and folding. We performed single cell sequencing to reveal the change of cell types in single cell level. Method: Single cell isolation was prepared from P0 telencephalic tissue of wild-type (WT) and serpina3f/+;Nestin-Cre mice. Th...
ORGANISM(S): Mus musculus 
2021-01-26 | GSE165440 | GEO
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