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GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [RRBS]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52266 | biostudies-arrayexpress
GenomicsMaternal Nutrition Induces Pervasive Gene Expression Changes but no Detectable DNA Methylation Differences in the Liver of Adult Offspring [selected loci]
Aims: Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we aim to explore phenotypes induced by maternal obesity in a mouse model and examine gene ex...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-52267 | biostudies-arrayexpress
TranscriptomicsMre11 suppresses replication stress and gene amplification proficiency
Gene amplification, copy-number increases of particular genes and surrounding genomic segments, promotes cancer progression and acquired therapy resistance. Thus, understanding genetic traits that confer gene amplification proficiency is important. The primary step for gene amplification is sponta...
ORGANISM(S): Cricetulus griseus 
2015-03-05 | E-GEOD-59487 | biostudies-arrayexpress
TranscriptomicsResolution of Type 2 Diabetes Following Bariatric Surgery is Associated with Changes in Whole Blood Gene Expression
To investigate the effects of bariatric surgery on gene expression profile changes in whole blood in obese subjects with type 2 diabetes in a pilot study setting. Whole blood from eleven obese subjects with type 2 diabetes was collected in PAXgene tubes prior to and 6-12 months after bariatric surg...
ORGANISM(S): Homo sapiens 
2011-01-06 | E-GEOD-19790 | biostudies-arrayexpress
UnknownWDR34 mutations that cause short-rib polydactyly syndrome type III/severe asphyxiating thoracic dysplasia reveal a role for the NF-κB pathway in cilia.
Not available
S-EPMC3824112 | biostudies-literature
UnknownInternational Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: Retrospective Cohort Study.
Not available
S-EPMC8510151 | biostudies-literature
UnknownInternational electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium.
Not available
S-EPMC7438496 | biostudies-literature
UnknownPredicting EQ-5D-3L utility values from clinical data in a prospective cohort of kidney transplant recipients.
Not available
S-EPMC12929319 | biostudies-literature
UnknownInternational comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality.
Not available
S-EPMC9192605 | biostudies-literature
UnknownEmergency department outcome of elderly patients assisted by professional home services, the EPIGER study.
Not available
S-EPMC7507819 | biostudies-literature
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