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TranscriptomicsExpression defined classification of subtypes of diffuse large B cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) comprises molecularly distinct subgroups such as activated B-cell-like (ABC) and germinal center B-cell-like (GCB) DLBCLs. We previously reported that CD5(+) and CD5(-)CD10(+) DLBCL constitute clinically relevant subgroups. To determine whether these 2 subgroups...
ORGANISM(S): Homo sapiens 
2009-07-10 | E-GEOD-16920 | biostudies-arrayexpress
TranscriptomicsExpansion of HSC by AML1a
Mouse bone marrow cells were infected with retrovirus for doxycylin-controllable AML1a expression, and cultured in vitro. Cells were treated with doxycycline to silence AML1a expression or left untreated to keep AML1a expression on, and subjected to microarray analysis to profile transcripts AML1a i...
ORGANISM(S): Mus musculus 
2011-12-19 | E-MEXP-3179 | biostudies-arrayexpress
TranscriptomicsGenomic alterations of 332 malignant lymphoma using BAC array CGH analysis
Clonal heterogeneity in lymphoid malignancies has been recently reported in adult T-Cell lymphoma/leukemia, peripheral T-cell lymphoma, not otherwise specified, and mantle cell lymphoma (MCL). Our analysis was extended to other types of lymphoma including marginal zone lymphoma, follicular lymphom...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-54303 | biostudies-arrayexpress
TranscriptomicsClonal heterogeneity of mantle cell lymphoma revealed by array comparative genomic hybridization
The existence of clonal heterogeneity of mantle cell lymphoma based on genomic aberration evaluated by log2 ratio(clinical samples)
ORGANISM(S): Homo sapiens 
2012-07-30 | E-MTAB-1076 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of primary and metastatic clear cell renal cell carcinoma by array-based comparative genomic hybridization.
In this study, we investigated CNAs of 20 primary clear cell renal cell caricinomas (ccRCCs), 20 corresponding metastases and another subsets of 30 primary ccRCCs by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 primary ccRCCs, 20 corresponding metastases and anot...
ORGANISM(S): Homo sapiens 
2014-10-16 | E-GEOD-43477 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of gastric adenomas by array-based comparative genomic hybridization
In this study, we investigated CNAs of 20 gastric CIS (Vienna category 4.2) and 20 adenomas, including 7 low-grade adenomas (LGA; Vienna category 3) and 13 high-grade adenomas (HGA; Vienna category 4.1), by 244k oligonucleotide-based array comparative genomic hybridization (array CGH). 20 gastric ad...
ORGANISM(S): Homo sapiens 
2010-06-18 | E-GEOD-19574 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of 19 renal cell carcinoma samples from patients with end-stage renal disease
In this study, 19 tumor samples from patients with renal cell carcinoma (RCC)-end-stage renal disease (ESRD) were analyzed by array comparative genomic hybridization (array CGH) using the Agilent Whole Human Genome 4× Array. 19 cystic disease samples from patients with RCC-ESRD
ORGANISM(S): Homo sapiens 
2012-04-01 | E-GEOD-33117 | biostudies-arrayexpress
TranscriptomicsGenomic copy number aberrations of 11 gastric cancer cell lines
Genomic copy number aberrations of 11 gastric cancer cell lines were analyzed by 244k CGH array from Agilent Technologies. Based on this results, we separated the 11 cell lines into 2 groups, with and without copy number increase at chromosome 20q13 We performed array comparative genomic hybridizati...
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-67604 | biostudies-arrayexpress
TranscriptomicsGenomic profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization
In this study, we investigated CNAs of 40 tumor samples from 25 patients, including 15 metastatic primary tumor (MPT), paired neck lymph-node metastasis (LNM) and 10 non-metastatic primary tumor (NMPT), by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 15 MPT vs 15 LN...
ORGANISM(S): Homo sapiens 
2013-09-08 | E-GEOD-36942 | biostudies-arrayexpress
TranscriptomicsIntratumoral genomic heterogeneity in submucosal-invasive gastric cancer
In this study, we investigated CNAs of 59 tumor samples from 27 patients with submucosal-invasive gastric cancers (SMGC) by 44k oligonucleotide-based array comparative genomic hybridization (array CGH). 23 mucosal portion of SMGC vs 23 paired submucosal (SM) portion of SMGC, 9 SM portion vs 9 paired...
ORGANISM(S): Homo sapiens 
2012-01-20 | E-GEOD-26800 | biostudies-arrayexpress
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