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UnknownAn Integrated and Semiautomated Microscaled Approach to Profile Cis-Regulatory Elements by Histone Modification ChIP-Seq for Large-Scale Epigenetic Studies.
Not available
S-EPMC6844362 | biostudies-literature
UnknownA Semiautomated ChIP-Seq Procedure for Large-scale Epigenetic Studies.
Not available
S-EPMC7870284 | biostudies-literature
UnknownSingle-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma.
Not available
S-EPMC7372639 | biostudies-literature
TranscriptomicsGene expression analysis of TIL rich HPV driven head and neck tumours reveals a distinct B-cell signature when compared to HPV independent tumours.
Purpose: Human papilloma virus (HPV) associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than HPV(-) negative cancer. This may be due, in part, to the higher number of tumour infiltrating lymphocytes (TIL) in HPV(+) tumours. We used RNAseq to evaluate whether these differ...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-72536 | biostudies-arrayexpress
TranscriptomicsTargeting microRNAs for asthma treatment
Profiling miRNA expression in cells that directly contribute to human disease pathogenesis is likely to aid the discovery of novel drug targets and biomarkers. However, tissue heterogeneity and the limited amount of human diseased tissue available for research purposes present fundamental difficulti...
ORGANISM(S): Homo sapiens 
2013-01-11 | E-GEOD-31030 | biostudies-arrayexpress
GenomicsIdentification of a novel Aire-regulating cis-regulatory element using H3K27ac ChIP-seq
Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cells (mTECs), the Autoimmune regulator (Aire) gene plays an essential role in this process by driving the expression of a diverse set of tissue-specific antigens (TSAs), which are presented and help tol...
ORGANISM(S): Mus musculus 
2015-10-23 | E-GEOD-74257 | biostudies-arrayexpress
UnknownCytotoxic CD4+ tissue-resident memory T cells are associated with asthma severity.
Not available
S-EPMC10964988 | biostudies-literature
GenomicImpact of Genetic Polymorphisms on Human Immune Cell Gene Expression

While many genetic variants have been associated with risk for human diseases, how these variants affect gene expression in various cell types remains largely unknown. To address this gap, the DICE (Database of Immune Cell Expression, Expression quantitative trait loci (eQTLs) and Epigenomics) pr...

phs001703 | dbGaP
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