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TranscriptomicsGene expression analysis of cervical cancer progression
Affymetrix-U133-plus2.0-based gene expression analysis of laser-captured epithelium from 128 cervical tissue specimens from women enrolled in SUCCEED Cervical cancer (CC) is the second most frequent cancer in women and the third leading cause of cancer death in women worldwide. Our analysis of norma...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-63514 | biostudies-arrayexpress
TranscriptomicscRel sang
NF-kB is a transcriptional factor that consists in homo and heterodimers of the large family of Rel subunits. Among the most important functions for NF-kB, initiation of immunological/inflammatory responses and regulation of cell proliferation/apoptosis which are the major features of severe infecti...
ORGANISM(S): Mus musculus 
2011-10-14 | E-MEXP-2944 | biostudies-arrayexpress
TranscriptomicsEarly transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients
This study determined key transcriptional signatures associated with HCV recurrence and eventual development of severe liver disease in infected transplant patient liver biopsies over time following transplant. We identified molecular signatures associated with severe fibrosis and liver injury prior...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-34798 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains
Gene expression patterns were investigated in well-defined genetically cerebral malaria-resistant (CM-R) and cerebral malaria-susceptible (CM-S) mouse strains. cDNA microarrays were used to search for differentially expressed genes in mouse brain. Four mouse strains, known to differ in susceptibilit...
ORGANISM(S): Mus musculus 
2005-06-30 | E-MEXP-370 | biostudies-arrayexpress
TranscriptomicsAK2 deficiency affects human hematopoiesis
Reticular dysgenesis (RD) is a human Severe Combined Immunodeficiency mainly characterized by a profound neutropenia and lymphopenia. This pathology is due to mutations in the adenylate kinase 2 (AK2) gene, resulting in the loss of AK2 protein expression. AK2 is a mitochondrial protein, which regula...
ORGANISM(S): Homo sapiens 
2015-06-21 | E-MTAB-2680 | biostudies-arrayexpress
TranscriptomicsRNA-seq of RBC depleted whole blood from COVID-19 patients and controls
Red blood cells (RBC) depleted whole blood from COVID-19 patients and controls was harvested and processed in order to performed 10X single cell RNA-seq. For COVID-19 patients 2 samples 10 days a part were analyzed.
ORGANISM(S): Homo sapiens 
2020-08-21 | E-MTAB-9221 | biostudies-arrayexpress
MetabolomicsInhibition of stress resilience and adult hippocampal neurogenesis by platelet-derived LPA16:0 in anxiety

Anxiety is an aggravating comorbidity of many psychiatric disorders that is often underdiagnosed and undertreated, and little is known on the mechanisms underlying its regulation. Here, we find that serum LPA16:0 abundance increases with trait anxiety in both humans and mice; while high LPA16:0 l...

2026-02-05 | MTBLS13589 | MetaboLights
UnknownSystemic Amyloid A Amyloidosis in Island Foxes (Urocyon littoralis): Severity and Risk Factors.
Not available
S-EPMC4871602 | biostudies-literature
UnknownInfected erythrocytes and plasma proteomics reveals a specific protein signature of severe malaria
Not available
S-SCDT-10_1038-S44321-023-00010-0 | biostudies-other
TranscriptomicsA novel IRES identified in DMD results in a functional N-truncated dystrophin, providing a potential route to therapy for patients with 5’ mutations.
Purpose: Ribosome profiling and RNA-Seq were used to map the location and abundance of translating ribosomes on human skeletal muscle transcripts from a patient with Becker muscular dystrophy. Methods: Tissue homogenates were prepared from frozen sections of a muscle biopsy obtained from a patient w...
ORGANISM(S): Homo sapiens 
2014-08-02 | E-GEOD-56148 | biostudies-arrayexpress
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