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MetabolomicsGut Bacteroides act in a microbial consortium to cause susceptibility to severe malaria

Malaria, caused by Plasmodium species, remains a significant cause of morbidity and mortality globally. Gut bacteria can influence the severity of malaria, but the contribution of specific bacteria to the risk of severe malaria is unknown. Here, multiomics approaches demonstrate specific...

2023-09-13 | MTBLS3449 | MetaboLights
GenomicsDefining the Inflammation and Immunity Transcriptome in Severe Malarial Anemia for Immunotherapeutic Discovery
Defining the Inflammation and Immunity Transcriptome in Severe Malarial Anemia for Immunotherapeutic Discovery
PRJNA1074811 | ENA
GenomicsTranscriptomic Profiling of Blood-Stage Plasmodium falciparum in Children with Severe Malarial Anemia
Transcriptomic Profiling of Blood-Stage Plasmodium falciparum in Children with Severe Malarial Anemia
PRJNA1405121 | ENA
TranscriptomicsDefining the Inflammation and Immunity Transcriptome in Severe Malarial Anemia for Immunotherapeutic Discovery
Malaria continues to pose a significant public health threat, with millions of cases and hundreds of thousands of deaths reported annually, primarily in sub-Saharan Africa. The disease disproportionally affects children under five years of age residing in holoendemic Plasmodium falciparum transmissi...
ORGANISM(S): Homo sapiens 
2024-04-16 | GSE255403 | GEO
UnknownDeveloping a novel risk prediction model for severe malarial anemia.
Not available
S-EPMC5732579 | biostudies-literature
Genomicscynomolgus and rhesus macaques infected with plasmodium coatneyi
malaria infection in rhesus and cynomolgus macaques differ in disease progression toward severe malarial anemia
PRJNA504663 | ENA
TranscriptomicsTranscript data from a severe malaria study
Transcript data detailing human transcription in severe malaria cases and uncomplicated malaria controls in a Mali study. Severe malaria cases were either cerebral malaria, severe malarial anemia, or concurrent cerebral malaria and severe malarial anemia disease.
ORGANISM(S): Homo sapiens 
2025-03-25 | GSE289197 | GEO
TranscriptomicsTranscriptomic Profiling of Blood-Stage Plasmodium falciparum in Children with Severe Malarial Anemia
Malaria is a major global health threat, with millions of cases and hundreds of thousands of deaths reported annually, primarily in sub-Saharan Africa. Children under five years of age residing in holoendemic Plasmodium falciparum transmission regions are the most vulnerable to malaria, accounting f...
ORGANISM(S): Plasmodium falciparum 
2026-06-07 | GSE316842 | GEO
UnknownSuppression of a novel hematopoietic mediator in children with severe malarial anemia.
Not available
S-EPMC2737985 | biostudies-literature
UnknownSerologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria.
Not available
S-EPMC9393435 | biostudies-literature
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