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ModelsShah2020 - Predicting Human Liver Microsomal Stability of small molecules
The Human Liver Microsomal assay takes into account the liver-mediated drug metabolism to assess the stability of a compound in the human body. The NIH-NCATS group took a proprietary dataset of 4300 compounds with its associated HLM (in vitro half-life; unstable ≤  30 min, stable >30 min) and used i...
2024-05-13 | MODEL2405130005 | BioModels
Machine Learning Model FAIR-AIML Ersilia 
ModelsShah2020 - Predicting liver cytosol stability of small molecules.
The human liver cytosol stability model is used for predicting the stability of a drug in the cytosol of human liver cells, which is beneficial for identifying potential drug candidates early during the drug discovery process. If a drug compound is quickly absorbed, it may not reach the intended tar...
2024-04-22 | MODEL2404220005 | BioModels
Machine Learning Model FAIR-AIML Ersilia 
UnknownInitiation or switch to insulin degludec/insulin aspart in adults with type 2 diabetes in India: Results from a prospective, non-interventional, real-world study.
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S-EPMC11504744 | biostudies-literature
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