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TranscriptomicsHnRNPLL is a global regulator of alternative splicing in activated T cells
HnRNPLL was identified as a critical regulator of CD45 alternative splicing in a lentiviral shRNA screen. RNAi-mediated depletion of hnRNPLL eliminated the activation-induced induced transition from the CD45RA to the CD45RO isoform. HnRNPLL is induced during the process of T cell activation, raising...
ORGANISM(S): Homo sapiens 
2010-09-15 | E-GEOD-11834 | biostudies-arrayexpress
Unknown(1E,4E)-1,5-Bis(thio-phen-3-yl)penta-1,4-dien-3-one.
Not available
S-EPMC3200598 | biostudies-literature
UnknownZwitterionic 1-{(1E)-[(4-hy-droxy-phen-yl)iminio]meth-yl}naphthalen-2-olate: crystal structure and Hirshfeld surface analysis.
Not available
S-EPMC5683488 | biostudies-literature
UnknownCrystal structure of 2-{(E)-[(2-hy-droxy-phen-yl)iminium-yl]meth-yl}-4-methyl-phenolate.
Not available
S-EPMC4420074 | biostudies-literature
UnknownA clinical trial comparing Lanconone® with ibuprofen for rapid relief in acute joint pain.
Not available
S-EPMC4823836 | biostudies-literature
Transcriptomicsnaive/activated ANOVA group
In order to identify genes with differential gene expression or alternative splicing between the groups naive and activated we study 4 hybridizations on the Human Exon 1.0 ST array using mixed model analysis of variance. 1904 genes with significant gene expression differences between the groups and...
ORGANISM(S): Homo sapiens 
2010-09-21 | E-GEOD-11832 | biostudies-arrayexpress
TranscriptomicsLL-sh4/uninfected/shGFP ANOVA group
In order to identify genes with differential gene expression or alternative splicing between the groups LL-sh4, uninfected, and shGFP we study 6 hybridizations on the Human Exon 1.0 ST array using mixed model analysis of variance. 842 genes with significant gene expression differences between the g...
ORGANISM(S): Homo sapiens 
2010-09-15 | E-GEOD-11833 | biostudies-arrayexpress
UnknownGenome-wide occupancy reveals the localization of H1T2 (H1fnt) to repeat regions and a subset of transcriptionally active chromatin domains in rat spermatids.
Not available
S-EPMC7788777 | biostudies-literature
TranscriptomicsCTCF promotes RNA pol II pausing and links DNA methylation to alternative splicing [RNA-Seq]
The goal of this study was to investigate the role of intragenic CTCF in alternative pre-mRNA splicing through a combined CTCF-ChIP-seq and RNA-seq approach. CTCF depletion led to decreased inclusion of weak upstream exons. CTCF ChIP-seq was performed in BJAB and BL41 B cell lines and normalized rel...
ORGANISM(S): Homo sapiens 
2011-10-06 | E-GEOD-31486 | biostudies-arrayexpress
TranscriptomicsSRS endotype assignment of septic shock patients from the VANISH randomised trial
The aim of the experiment was to assign patients enrolled in the VANISH randomised trial to sepsis response signature (SRS) endotypes based on a previously published gene expression signature, in order to test for differential responses to treatment. VANISH was a double-blind randomised clinical tri...
ORGANISM(S): Homo sapiens 
2022-07-12 | E-MTAB-7581 | biostudies-arrayexpress
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