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TranscriptomicsETV1 knockdown in GIST cell lines
ETV1 is highly expressed in GIST cells and required for their survival and growth. To identify genes and pathways regulated by ETV1 in GIST, we performed expression profiles of GIST cells after ETV1 knockdown. Two GIST cell lines (GIST48 and GIST882) were infected in duplicate with three shRNA virus...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-19396 | biostudies-arrayexpress
GenomicsMapping of ETV1 genomic binding sites in gastrointestinal stromal tumor (GIST).
ETV1 is highly expressed in GIST and their presumed precursors--the interstitial cells of Cajal. ETV1 is required for survival for both GIST and ICC and regulates GIST signature genes. Here, using Illumina-Solexa based next-generation sequencing of ETV1 chromatin immunoprecipates (ChIP-Seq), we defi...
ORGANISM(S): Homo sapiens 
2010-10-14 | E-GEOD-22441 | biostudies-arrayexpress
TranscriptomicsImatinib Treatment of GIST882
Gastrointestinal Stromal Tumor frequently harbor mutations in the KIT receptor tyrosine kinase and depend on its activity for growth. This underlies the efficacy of imatinib, a inhibitor of KIT activity, in GIST management. GIST882 is a patient derived GIST cell line that harbor a K640E exon 13 KIT ...
ORGANISM(S): Homo sapiens 
2010-10-13 | E-GEOD-22433 | biostudies-arrayexpress
UnknownEffects of CYP2B6 and CYP1A2 Genetic Variation on Nevirapine Plasma Concentration and Pharmacodynamics as Measured by CD4 Cell Count in Zimbabwean HIV-Infected Patients.
Not available
S-EPMC4575538 | biostudies-literature
UnknownDoes a history of sexual and physical childhood abuse contribute to HIV infection risk in adulthood? A study among post-natal women in Harare, Zimbabwe.
Not available
S-EPMC6319705 | biostudies-literature
UnknownA systematic review of antimicrobial resistance in Neisseria gonorrhoeae and Mycoplasma genitalium in sub-Saharan Africa.
Not available
S-EPMC9333409 | biostudies-literature
UnknownZimbabwe's national third-line antiretroviral therapy program: Cohort description and treatment outcomes.
Not available
S-EPMC7051055 | biostudies-literature
UnknownHIV-1 Genetic Diversity and Natural Polymorphisms of the Integrase Gene in Integrase Inhibitor-Naive Patients in Harare, Zimbabwe.
Not available
S-EPMC8817709 | biostudies-literature
UnknownDeveloping a pricing model for general medical consultation services among private consulting rooms in Harare, Zimbabwe.
Not available
S-EPMC12700376 | biostudies-literature
UnknownTreatment outcomes in HIV infected patients older than 50 years attending an HIV clinic in Harare, Zimbabwe: A cohort study.
Not available
S-EPMC8189507 | biostudies-literature
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