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ModelsSmith2010_Foxo_PTMs_AgeingRelatedSignallingPathway_C
This a model from the article: Modelling the response of FOXO transcription factors to multiple post-translational modifications made by ageing-related signalling pathways. Smith GR, Shanley DP. PLoS One. 2010 Jun 14;5(6):e11092. 20567500 , ...
2005-01-01 | MODEL1112260002 | BioModels
ModelsSmith2013 - Regulation of Insulin Signalling by Oxidative Stress
Smith2013 - Regulation of Insulin Signalling by Oxidative Stress The model describes insulin signalling (in rodent adipocytes), which includes in addition to the core pathway, the transcriptional feedback through the Forkhead box type O (FOXO) transcription factor and interaction w...
2024-09-02 | BIOMD0000000474 | BioModels
ModelsSonntag2012 - mTOR model - IRS dependent regulation of AMPK by insulin
Sonntag2012 - mTOR model - IRS dependent regulation of AMPK by insulin TSC1-TSC2 complex has two states: 1) active (TSC1_TSC2_pS1387), regulated by AMPK_pT172; 2) inactive (TSC1_TSC2_pT1462) regulated by Akt_pT308. Particularly, mTORC1 is inhibited by TSC1_TSC2 in active state. AMPK is activated at ...
2024-09-02 | BIOMD0000000580 | BioModels
ModelsMartinez-Guimera2017 - Generic redox signalling model without negative regulation (Model 1)
Martinez-Guimera2017 - Generic redox signalling model without negative regulation (Model 1) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez Guimera A, Welsh CM, Proctor CJ, McArdle A, Shanley...
MODEL1710260000 | BioModels
ModelsMartinez-Guimera2017 - Generic redox signalling model with negative feedback regulation (Model 2)
Martinez-Guimera2017 - Generic redox signalling model with negative feedback regulation (Model 2) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez Guimera A, Welsh CM, Proctor CJ, McArdle A, S...
MODEL1710260001 | BioModels
ModelsMartinez-Guimera2017 - Generic redox signalling model with negative feedforward regulation (Model 3)
Martinez-Guimera2017 - Generic redox signalling model with negative feedforward regulation (Model 3) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez Guimera A, Welsh CM, Proctor CJ, McArdle A...
MODEL1710260002 | BioModels
ModelsMartinez-Guimera2017 - Generic negative feedback circuit (Model 4)
Martinez-Guimera2017 - Generic negative feedback circuit (Model 4) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez Guimera A, Welsh CM, Proctor CJ, McArdle A, Shanley DP. Mech. Ageing Dev. ...
MODEL1710260003 | BioModels
ModelsMartinez-Guimera2017 - Generic negative feedforward circuit (Model 5)
Martinez-Guimera2017 - Generic negative feedforward circuit (Model 5) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez Guimera A, Welsh CM, Proctor CJ, McArdle A, Shanley DP. Mech. Ageing De...
MODEL1710260004 | BioModels
ModelsMartinez-Guimera2017 - Generic redox signalling model with negative feedback regulation (Model 2)
Martinez-Guimera2017 - Generic redox signalling model with negative feedback regulation (Model 2) This model is described in the article: 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. Martinez...
2020-03-20 | MODEL2001080001 | BioModels
ModelsDallePezze2014 - Cellular senescene-induced mitochondrial dysfunction
DallePazze2014 - Cellular senescene-induced mitochondrial dysfunction This model is described in the article: Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions. Dalle Pezze P, Nelson G, Otten EG, Korolchuk VI, Kirkwood TB, von...
2024-09-02 | BIOMD0000000582 | BioModels
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