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To investigate the impact of pathogenic immune stimulation on the lipid droplet (LD) proteome of turbot (Scophthalmus maximus), turbot were intraperitoneally injected with PBS (XA01292LQ_P), wild-type Edwardsiella piscicida EIB202 (XA01292LQ_W), or inactivated E. piscicida EIB202 (XA01292LQ_T). Live...
ORGANISM(S): Scophthalmus maximus 
2024-11-21 | PXD047605 | Pride
This study aims to investigate lysine acetylation sites on the H-NS protein in Edwardsiella piscicida. The H-NS protein was first purified, then subjected to SDS-PAGE, followed by gel band excision and LC-MS/MS identification.
ORGANISM(S): Edwardsiella tarda EIB202 
2024-05-24 | PXD047152 | Pride
The secretion protein of the important virulence factor T6SS has not been fully identified yet. In order to identify the novel T6SS secreted protein of important fish pathogens, we chose the quantitative proteomics method of 4D label free.
ORGANISM(S): Edwardsiella piscicida 
2024-12-28 | PXD050280 | Pride
To figure out the intracellular function of YfiD, HA-tagged YfiD or Mock was expressed in the HeLa cell line. Subsequently, the lysates of HeLa-YfiD or HeLa-Mock cells were immunoprecipitated with anti-HA beads followed by LC-MS/MS analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-01-15 | PXD047656 | Pride
This assay aims to identify the composition of an unidentified protein band (~10 kDa) in Edwardsiella piscicida’s extracellular proteins (ECPs). To make this end, this protein band was cut, followed by gel band excision and LC-MS/MS identification.
ORGANISM(S): Edwardsiella tarda EIB202 
2024-01-15 | PXD048313 | Pride
Lipid droplets (LDs), as innate immune hubs, function in the front line of antimicrobial defense involved in the ongoing host-pathogen arms race. Particularly for intracellular bacterial pathogens, the endowed capacity to resist host LDs can effectively facilitate pathogen in vivo colonization and e...
2025-07-04 | MTBLS9590 | MetaboLights

Lipids, fundamental constituents of cell membranes, cellular energy carriers, and signaling molecules, play a pivotal role in the interaction between pathogens and hosts. During microbial infections, lipids not only fuel the activation of the immune system but also, acting as signaling molec...

2025-07-05 | MTBLS12678 | MetaboLights
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