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TranscriptomicsGenome-wide profiling of PARP1 reveals an interplay with gene regulatory regions and DNA methylation
To address the global impact of PARP-1 on DNA methylation, we treated cells with PJ34 (PARylation inhibitor) and isolated genomic DNA from vehicle and PJ34 treated cells. This DNA was bisulfite treated and hybridized to the Illumina infinium Methylation 450 Beadchip. We next used these RNA-seq data ...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-61744 | biostudies-arrayexpress
ProteomicsProteomic landscape of plasma and plasma-derived sEVs and lEVs in uveitis and posterior scleritis
Uveitis and posterior scleritis are sight-threatening diseases with undefined pathogenesis, accurate diagnosis remains challenging. Here, two plasma-derived extracellular vesicle (EV) subpopulations, small and large EVs, were obtained from patients with uveitis and posterior scleritis and subjected ...
ORGANISM(S): Homo Sapiens 
2022-09-19 | PXD036844 |
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