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TranscriptomicsHuman CA2 ES cells undergoing stepwise differentiation to airway epithelium and challenged with TNFa and LPS
This study examines the innate immune response of human pluripotent stem cell derived airway epithelium. Immune challenge was performed with TNF-alpha or bacterial lipopolysaccharide (LPS) Airway epithelium differentiated from the ES line CA2 was compared to paired differentiated cells stimulated wi...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-59472 | biostudies-arrayexpress
TranscriptomicsHematopoietic stem cells progressively deficient of glycogen synthase kinase initiate a pre-neoplastic state required for evolution to acute leukemia
The cellular origin and molecular progression towards aggressive cancers such as acute myeloid leukemia (AML) remain elusive. Clinically, Myelodysplastic syndromes (MDS) and related myeloproliferative neoplasias (MPN) disorders1-5 are believed to present as a precursor stage to lethal AML developmen...
ORGANISM(S): Mus musculus 
2016-01-11 | E-GEOD-53352 | biostudies-arrayexpress
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