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TranscriptomicsRejuvenation of pluripotent stem cells by frequent activation of Zscan4, Part B
The gold standard for examining pluripotency of stem cells is to see whether cells can contribute to entire body of animals. Here we show that the increased frequency of Zscan4 activation in mouse ES cells not only enhances, but also maintains their developmental potency in long-term cell culture. A...
ORGANISM(S): Mus musculus 
2013-06-12 | E-GEOD-26162 | biostudies-arrayexpress
TranscriptomicsRejuvenation of pluripotent stem cells by frequent activation of Zscan4, Part A
The gold standard for examining pluripotency of stem cells is to see whether cells can contribute to entire body of animals. Here we show that the increased frequency of Zscan4 activation in mouse ES cells not only enhances, but also maintains their developmental potency in long-term cell culture. A...
ORGANISM(S): Mus musculus 
2013-06-12 | E-GEOD-15604 | biostudies-arrayexpress
TranscriptomicsDefining Developmental Potency and Cell Lineage Trajectories by Expression Profiling of Differentiating Mouse ES Cells
Biologists rely on morphology, function, and specific markers to define the differentiation status of cells. Transcript profiling has expanded the repertoire of these markers by providing the snapshot of cellular status that reflects the activity of all genes. However, such data have been used only ...
ORGANISM(S): Mus musculus 
2008-12-27 | E-GEOD-11523 | biostudies-arrayexpress
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