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TranscriptomicsAMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
Faithful execution of developmental programs relies on the acquisition of unique cell identities from pluripotent progenitors, a process governed by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-specific transcriptional outputs. Despite growing evidence that m...
ORGANISM(S): Mus musculus 
2016-03-09 | E-GEOD-77705 | biostudies-arrayexpress
ProteomicsQuantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
Metformin is the front-line treatment for type 2 diabetes worldwide. It acts via effects on glucose and lipid metabolism in metabolic tissues, leading to enhanced insulin sensitivity. Despite significant effort, the molecular basis for metformin response remains poorly understood, with a limited nu...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-07 | MSV000084429 | MassIVE
TranscriptomicsTranscription profiling of murine livers after resveratrol treatment of mice on a high-calorie diet
Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including yeast, worms, and flies. In these organisms, lifespan extension is dependent on Sir2, a conserved deacetylase proposed to underlie the beneficial effects of caloric restriction (CR). Here we show that resveratr...
ORGANISM(S): Mus musculus 
2008-06-21 | E-GEOD-6089 | biostudies-arrayexpress
UnknownAssociation of Convalescent Plasma Therapy With Survival in Patients With Hematologic Cancers and COVID-19.
Not available
S-EPMC8377563 | biostudies-literature
UnknownRacial Disparities in COVID-19 Outcomes Among Black and White Patients With Cancer.
Not available
S-EPMC8961318 | biostudies-literature
UnknownA Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance.
Not available
S-EPMC7598547 | biostudies-literature
UnknownAssessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States.
Not available
S-EPMC8728628 | biostudies-literature
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