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TranscriptomicsA TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression
We sequenced mRNA from 3 biological replicates each of A549 lung adenocarcinoma cell lines expressing shRNA against GFP (control), PRMT5, or MEP50. We then determined differential gene expression. Transcriptome analysis of mRNA testing the role of PRMT5 and MEP50 by knockdown in A549 human lung aden...
ORGANISM(S): Homo sapiens 
2016-06-09 | E-GEOD-80182 | biostudies-arrayexpress
UnknownRinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.
Not available
S-EPMC6716522 | biostudies-literature
MetabolomicsThe GNMT N-terminus Couples Folate Feedback to Methyl-donor Homeostasis
Maintenance of S-adenosylmethionine (SAM) homeostasis is essential for methylation of biomolecules, nucleotide and polyamine synthesis, and redox balance. While all methyltransferases consume SAM, only a subset of highly tissue specific methyltransferases regulates methylation potential. Among them,...
2026-08-18 | MTBLS15161 | MetaboLights
UnknownPredicting the risk of iliofemoral vascular complication in complex transfemoral-TAVR using new generation transcatheter devices.
Not available
S-EPMC10357287 | biostudies-literature
UnknownLipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol.
Not available
S-EPMC8822604 | biostudies-literature
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