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TranscriptomicsGene Set Enrichment Analysis reveals lineage relationships between mouse and human gliomas and identifies stem cells and PNET as distinct entities
Murine and human genome-wide microarray expression profiles (including GSE19404) were compared using Partek and Gene Set Enrichment Analysis (GSEA) in order to identify similarities. A murine PNET-like tumour by morphology was found to resemble human ATRT, whereas experimental glioma resembled a par...
ORGANISM(S): Mus musculus 
2013-07-29 | E-GEOD-42515 | biostudies-arrayexpress
GenomicsLigand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating Retinoic Acid Receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presence of the ret...
ORGANISM(S): Mus musculus 
2010-12-10 | E-GEOD-19409 | biostudies-arrayexpress
TranscriptomicsTiling path analysis to map chromatin anchors within the human Major Histocompatability Complex region from B-lymphoblastoid cells and IFNg+/IFNg- treated fibroblasts
Mapping of chromatin anchors within the human Major Histocompatability Complex (MHC) region from B-lymphoblastoid cells and IFNg+/IFNg- treated fibroblasts.
ORGANISM(S): Homo sapiens 
2008-10-01 | E-MEXP-1793 | biostudies-arrayexpress
GenomicsChromatin landscape of progenitor motor neurons [ChIP-seq]
Progenitor motor neurons can be generated with high-efficiency by differentiating ES cells in vitro in the presence of retinoic acid and hedgehog signalling. Here, we characterize the chromatin landscape associated with progenitor motor neurons (pMNs) in order to assess how histone modification doma...
ORGANISM(S): Mus musculus 
2013-07-04 | E-GEOD-39434 | biostudies-arrayexpress
TranscriptomicsPrincipal components of embryonic stem cell pluripotency
To decipher gene regulatory networks, we used systematic suppression of 97 transcription factors (TFs) and 7 other genes with shRNA in mouse embryonic stem (ES) cells, followed by global gene expression profiling. Meta-analysis of these data together with the earlier data obtained by the induction o...
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-26520 | biostudies-arrayexpress
GenomicsHoxc9 ChIP-seq in differentiating motor neurons
The expression of v5-tagged Hoxc9 is induced and ChIP-seq is used to profile genome-wide occupancy in differentiating motor neurons The differentiation of ventral motor neurons is induced by treating embryonic stem cell cultures with retinoic acid and hedgehog signaling. Here, ChIP-seq is used to pr...
ORGANISM(S): Mus musculus 
2010-09-08 | E-GEOD-21812 | biostudies-arrayexpress
ProteomicsS.enterica - Whole organism, SC (Adkins,mcp,2006)
abundance based on Spectral counting, Interaction consistency score: 11.4, Coverage: 56
ORGANISM(S): 99287 
2006-00-00 | 2856723965 | PAXDB
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