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TranscriptomicsTranscription profiling of skin samples from atopic dermatitis patients before and after treatment with cyclosporine A
After 2 and 12 weeks of treatment, we observed significant reductions of 51% and 72%, respectively, in SCORAD scores. Clinical improvements were associated with significant gene expression changes in lesional but also nonlesional skin, particularly reductions in levels of TH2-, TH22-, and some TH17-...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-58558 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of skin from patients with atopic dermatitis before and after treatment with narrow-band UVB radiation
Background: Atopic dermatitis (AD) is a common inflammatory skin disease exhibiting a predominantly Th2/"T22" immune activation and a defective epidermal barrier. Narrow-band UVB (NB-UVB) is considered an efficient treatment for moderate to severe AD. In psoriasis, NB-UVB has been found to suppress ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-27887 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of acute and chronic atopic dermatitis compared to normal skin
Atopic dermatitis (AD) is a common disease, with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in lack of specific treatments. The prevailing view is that AD is a biphasic, T-cell polarized disease, with Th2 predominating acute AD, and a switch to Th1 ...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-36842 | biostudies-arrayexpress
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