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ProteomicsDifferences of phosphoproteome between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-08 | PXD027078 | JPOST Repository
ProteomicsDifferences of proteome between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-08 | PXD027079 | JPOST Repository
ProteomicsDifferences in binding partners between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-07 | PXD027083 | JPOST Repository
ProteomicsDifferences in protein domains between c-MYC and L-MYC during cellular reprogramming
MYC proteins (c-MYC, n-MYC, and L-MYC) are essential for improving reprogramming efficiency. L-MYC can generate iPSC colonies more efficiently than c-MYC. Still, it remains unknown what is the functional differences between c-MYC and L-MYC during cellular reprogramming. In this study, we performed p...
ORGANISM(S): Homo Sapiens (human) 
2022-01-07 | PXD027086 | JPOST Repository
UnknownReduced MLH3 Expression in the Syndrome of Gan-Shen Yin Deficiency in Patients with Different Diseases.
Not available
S-EPMC5634572 | biostudies-literature
UnknownCD40 Pathway and IL-2 Expression Mediate the Differential Outcome of Colorectal Cancer Patients with Different CSF1R c.1085 Genotypes.
Not available
S-EPMC8622906 | biostudies-literature
UnknownGermline MLH1 and MSH6 mutations from two Lynch syndrome families identified in a patient with early-onset of endometrial cancer: A case report.
Not available
S-EPMC10990849 | biostudies-literature
UnknownInnate Immune Responses of Vaccinees Determine Early Neutralizing Antibody Production After ChAdOx1nCoV-19 Vaccination.
Not available
S-EPMC8822242 | biostudies-literature
UnknownSingle-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.
Not available
S-EPMC12278398 | biostudies-literature
MetabolomicsPRODH regultes naive pluripotency by influencing mitochondrial oxidative phosphorylation (Untargeted metabolomics)

Naïve human embryonic stem cells (hESCs) that resemble the pre-implantation epiblasts are fueled by a combination of aerobic glycolysis and oxidative phosphorylation, but their mitochondrial regulators are poorly understood. Here we report that, proline dehydrogenase (PRODH), a mitochondria-local...

2024-02-12 | MTBLS7840 | MetaboLights
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