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Lappaol F, a natural lignin isolated from the seeds of Arctium lappa L., was previously shown to have an inhibitory effect on tumour cells and might be a promising drug candidate for cancer chemotherapy. In the present study, human colon cancer cell line SW480 was treated with Lappaol F, and quantit...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD017872 | Pride
Analyses of differential gene expression analyses from intact versus castrated Nkx3.1CE2/+ or Nkx3.1CE2/+; Ptenf/f mice Total RNA isolated form phenotypically wild-type (intact) Nkx3.1CE2/+ (n = 3), intact Nkx3.1CE2/+; Ptenf/f (n = 6), and castrated Nkx3.1CE2/+; Ptenf/f (n = 6) prostate. Please con...
ORGANISM(S): Mus musculus 
Anaysis of the response to different therapeutic agents at the transcriptional level. The design of the experiment allows to determine how the comnination target therapy (Rapamycin + PD0325901) treatment shifted the transcriptome towards a less aggressive or even a wild type phenotype. It also allow...
ORGANISM(S): Mus musculus 
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