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TranscriptomicsSelective demethylation and altered gene expression are associated with ICF Syndrome in human induced pluripotent stem cells and mesenchymal stem cells
Immunodeficiency, Centromeric Instability, and Facial Anomalies Type I (ICF1) Syndrome is a rare genetic disease caused by mutations in DNMT3B, a de novo DNA methyltransferase. However, the molecular basis of how DNMT3B-deficiency leads to ICF1 pathogenesis is unclear. Induced pluripotent stem cell ...
ORGANISM(S): Homo sapiens 
2014-11-17 | E-GEOD-46030 | biostudies-arrayexpress
TranscriptomicsRadiation-induced changes in gene expression in the silkworm revealed by serial analysis of gene expression
These results provide valuable information for understanding the mechanisms of radiation-induced changes in gene expression.
ORGANISM(S): Bombyx mori 
2005-06-20 | E-GEOD-2689 | biostudies-arrayexpress
TranscriptomicsX-inactivation in hESCs
X chromosome inactivation (XCI) is a dosage compensation mechanism in female cells to regulate X-linked gene expression. We report here that subcultures from established lines of female hESCs displayed variations (0-100%) in the expression of XCI markers such as XIST RNA coating and enrichment of h...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-9637 | biostudies-arrayexpress
ProteomicsExpression of ABC transporters negatively correlates with ectoine biosynthesis in Halomonas campaniensis under NaCl and ultraviolet mutagenesis treatments revealed by transcriptomic and proteomics combined analysis
Halomonas species are renowned for their production of organic compatible solutes, particularly ectoine. However, the identification of key regulatory genes governing ectoine production in Halomonas remains limited. In this study, we conducted a combined transcriptome-proteome analysis to unveil add...
ORGANISM(S): Halomonas 
2024-11-02 | PXD057477 |
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