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KRAS-mutant lung cancers frequently have inactivating mutations in LKB1, which enhances tumor growth, metastasis, and immune evasion. This study shows that LKB1 suppresses JNK stress signaling, and its loss in KRAS-mutant cells leads to JNK hyperactivation and apoptotic rewiring, making them sensiti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-06 | MSV000097246 | MassIVE
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | MassIVE
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | MassIVE
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