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MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
ProteomicsA novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional control in humans and mice
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-07 | PXD070427 | Pride
Meiotic recombination  zcwpw1–zcwpw2 complex  prdm9/zcwpw1/zcwpw2 system  ldha  ep300  lactylation 
ProteomicsA novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional control in humans and mice
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-01-07 | PXD068838 | Pride
Meiotic recombination  zcwpw1–zcwpw2 complex  prdm9/zcwpw1/zcwpw2 system  ldha  ep300  lactylation 
UnknownSurgeon influence on use of needle biopsy in patients with breast cancer: a national medicare study.
Not available
S-EPMC4164811 | biostudies-literature
UnknownSuppression of colorectal tumorigenesis by recombinant Bacteroides fragilis enterotoxin-2 in vivo.
Not available
S-EPMC5292333 | biostudies-literature
UnknownDifferent treatment strategies and molecular features between right-sided and left-sided colon cancers.
Not available
S-EPMC4458758 | biostudies-literature
MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
UnknownThe complete chloroplast genome of Epimedium wushanense T. S. Ying. (Berberidaceae), a traditional Chinese medicinal herb.
Not available
S-EPMC7748643 | biostudies-literature
ProteomicsCEP128 mutations impair spermatogenesis in humans and mice
The centrosome is a conserved eukaryotic organelle essential to the reproductive process, and centrosomal proteins are necessary for the components of the centrosome. However, few centrosomal proteins have been genetically linked to fertility, and the related molecular mechanisms remain unknown. Her...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD025330 | Pride
Cep128  infertility  spermatogenesis  centrosome 
ProteomicsDysfunction of CEP128 impairs spermatogenesis but not ciliogenesis in humans and mice
The centrosome is a conserved eukaryotic organelle essential for reproductive process, and centrosomal proteins (CEP) are necessary for composition of the centrosome. However, few CEPs have been genetically linked to fertility, and the related molecular mechanisms remains mysterious. Here, we identi...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD022731 | Pride
Cep128  infertility  spermatogenesis  centrosome 
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