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MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
MetabolomicsElevated temperature accelerates leaf senescence and promotes leaf nitrogen transport to improve rice grain protein synthesis
Elevated temperatures during grain filling severely constrain rice yield and quality. Although additional nitrogen can mitigate the adverse effects of elevated temperature, both factors increase grain protein content, and the underlying physiological mechanisms remain poorly understood. Here, we con...
2026-06-17 | MTBLS14777 | MetaboLights
ProteomicsProteomics of rice grains at normal temperature and enhanced temperature
Proteomics of rice grains on the 3rd, 6th, 9th, 12th and 15th day after flowering under the conditions of increased temperature and normal temperature
ORGANISM(S): Oryza Sativa Japonica Group 
PXD028032 |
ProteomicsEvaluation of the power of DeepRTAlign to eliminate missing values
Four samples were prepared: 293T digest (73%, 91%, 97% and 99%) offset by varied proportions (27%, 9%, 3% and 1%) of E.coli digest. 10 μg of 293T and E. coli mixtures were loaded each time and the DDA data were collected from six Orbitrap Exploris 480 mass spectrometers with the same settings.
ORGANISM(S): Homo Sapiens 
PXD046183 |
ProteomicsRT alignment test of DeepRTAlign using data under two gradients
Nano-flow LC-MS/MS analysis of 293T digest in two gradients.
ORGANISM(S): Homo Sapiens 
PXD044221 |
ProteomicsPerformance evaluation of DeepRTAlign using 293T-E.coli mixture datasets
10 μg 293T was spiked with different amounts ( 0.2, 0.3, 0.4, 0.5 μg) of E.coli. Performed the ablation analysis to evaluate the DNN model in DeepRTAlign. Compared DeepRTAlign with Quandenser. Compared DeepRTAlign with MaxQuant’s MBR and FragPipe’s MBR. Generalizability evaluation on simulated datas...
ORGANISM(S): Homo Sapiens Escherichia Coli 
PXD044222 |
ProteomicsReliability test of the QC module in DeepRTAlign
Micro-flow LC-MS/MS analysis of pure 293T or E.coli.
ORGANISM(S): Homo Sapiens 
PXD044223 |
ProteomicsDeepRTAlign: toward accurate retention time alignment for large cohort mass spectrometry data analysis
PRM datasets and Skyline results for the validation of ion-centric findings.
ORGANISM(S): Homo Sapiens 
PXD044224 |
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