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ProteomicsIn situ Analysis of Nanoparticle Soft Corona and Dynamic Evolution
How soft corona i.e., the protein corona’s outer layer contributes to “biological” identity of nanomaterials (NMs) is largely unknown due to a longstanding challenge in capturing protein composition of the soft corona in situ. We herein develop an in situ “Fishing” method that can monitor the dynami...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD033976 | Pride
Protein corona Mouse serum 
TranscriptomicsRNAseq changes in pre MAPKi treatment and post MAPKi resistance Melanomas
Melanoma resistance to MAPK- or T cell checkpoint-targeted therapies represents a major clinical challenge, and treatment failures of MAPK-targeted therapies due to acquired resistance often require salvage immunotherapies. We show that genomic analysis of acquired resistance to MAPK inhibitors reve...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-65185 | biostudies-arrayexpress
TranscriptomicsExpression changes in pre MAPKi treatment and post MAPKi resistance Melanomas
Melanoma resistance to MAPK- or T cell checkpoint-targeted therapies represents a major clinical challenge, and treatment failures of MAPK-targeted therapies due to acquired resistance often require salvage immunotherapies. We show that genomic analysis of acquired resistance to MAPK inhibitors reve...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-65184 | biostudies-arrayexpress
TranscriptomicsMethylation changes in pre MAPKi treatment and post MAPKi resistance Melanomas
Melanoma resistance to MAPK- or T cell checkpoint-targeted therapies represents a major clinical challenge, and treatment failures of MAPK-targeted therapies due to acquired resistance often require salvage immunotherapies. We show that genomic analysis of acquired resistance to MAPK inhibitors reve...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-65183 | biostudies-arrayexpress
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