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ProteomicsIDH3 serves as a redox switch that regulates energy metabolism and contractility in the heart under oxidative stress
Redox signaling and cardiac function are tightly linked. Still, it is largely unknown which specific protein targets are affected by reactive oxygen species (ROS) that underly the impaired inotropic effect in oxidative stress. Here, we combined a new chemogenetic mouse model (HMC HyPer-DAO transgeni...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-15 | PXD033119 | Pride
Ros Total reversible oxidation Hyper-dao mice 
ProteomicsIDH3 serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress
Redox signaling and cardiac function are tightly linked. Still, it is largely unknown which specific protein targets are affected by reactive oxygen species (ROS) that underly the impaired inotropic effect in oxidative stress. Here, we combined a new chemogenetic mouse model (HMC HyPer-DAO transgeni...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-21 | PXD037987 | Pride
Heart Mouse Hyperdao Redox proteomics 
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD020653 |
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