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The genomic DNA sample of AG-haESCs were compared to the C57BL/6J male mouse kidney by comparative genomic hybridization. The data confirmed that the haploid cells sustained genome integrity. The analysis was performed on a NimbleGen Mouse CGH 3x720K Whole-Genome Tiling Array to analyse the copy num...
ORGANISM(S): Mus musculus 
Haploid cells are amenable for genetic analysis because they contain only one set of chromosomes.Here,we report the derivation of haESCs from androgenetic blastocysts. These cells, which we designated AG-haESCs, express classical ESC markers, are pluripotent, and contribute to various tissues includ...
ORGANISM(S): Mus musculus 
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
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