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ProteomicsIdentifying Drug Targets with Thermal Proteome Profiling using IBT-16plex
Application of 16-plex iBT to drug target identification
ORGANISM(S): Homo Sapiens 
PXD041275 |
ProteomicsMouse Stromal Cells Confound Proteomic Characterization and Quantification of Xenograft Models
Accurate Protein Characterization and Quantification of Xenograft Tumors Requires Separating Human and Mouse Cells prior to Proteomics Profiling
ORGANISM(S): Homo Sapiens Mus Musculus 
2022-09-29 | PXD037070 |
ProteomicsMulti-parameter optimization of two common proteomics quantification methods for quantifying low-abundance proteins
To improve the sensitivity and accuracy of label-free quantification and tandem mass tags (TMT) labeling in quantifying low-abundance proteins, multi-parameter optimization was carried out using a complex 2-proteome artificial sample mixture for a series of steps from sample preparation to data anal...
ORGANISM(S): Homo Sapiens Mus Musculus 
2018-11-02 | PXD011574 |
ProteomicsEvaluation and minimization of nonspecific tryptic cleavages in proteomic sample preparation
Dataset for evaluation of nonspecific cleavages and artificial modifications using E.coli and A549 cells
ORGANISM(S): Homo Sapiens Escherichia Coli 
2020-01-19 | PXD017186 |
ProteomicsA brain signaling framework for stress-induced depression and ketamine treatment elucidated by phosphoproteomics
Depression is a common affective disorder characterized by significant and persistent low mood.Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, is reported to have a rapid and durable antidepressant effect.
ORGANISM(S): Mus Musculus 
2019-11-18 | PXD016302 |
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo Sapiens 
2019-11-19 | PXD016329 |
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