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TranscriptomicsERK1/2 in Ovarian Granulosa Cells are Essential for Female Fertility
A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals. Since the signaling molecules RAS and ERK1/2 are activated by a LH surge in granulosa cells of preovulatory follicles, we disrupted Erk1/2 in ...
ORGANISM(S): Mus musculus 
2009-03-20 | E-GEOD-15315 | biostudies-arrayexpress
TranscriptomicsHuman cathelicidin antimicrobial peptide LL37 effect on human neonatal epidermal keratinocytes (NHEKs).
Analysis of undifferentiated keratinocytes or differentiated keratinocytes stimulated with or without human cathelicidin antimicrobial peptide (CAMP) LL37. Results provide insight into the biological effects of CAMP on human keratinocytes. NHEKs were divided into two groups; low calcium (0.05 mM) an...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-49472 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cumulus cell oocyte complexes isolated at different time points of ovulation to identify differentially expressed genes.
Cumulus-oocyte complexes were isolated at seperate time-points to generate temporal complexes. Targets from two biological replicates at each time point (0h, 8h, 16h post-hCG treatment) were generated and the expression profiles were determined using Affymetrix GeneChip Mouse Genome 430 2.0 Arrays....
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-4260 | biostudies-arrayexpress
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