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TranscriptomicsAn Extended dsRBD with a Novel Zinc-Binding Motif Mediates Nuclear Retention of Fission Yeast Dicer
Dicer proteins function in RNA interference (RNAi) pathways by generating small RNAs (sRNAs). Here we report the solution structure of the C-terminal domain of Schizosaccharomyces pombe Dicer (Dcr1). The structure reveals an unusual double-stranded RNA binding domain (dsRBD) fold embedding a novel z...
ORGANISM(S): Schizosaccharomyces pombe 
2011-09-22 | E-GEOD-30586 | biostudies-arrayexpress
TranscriptomicsAn Extended dsRBD with a Novel Zinc-Binding Motif Mediates Nuclear Retention of Fission Yeast Dicer
Dicer proteins function in RNA interference (RNAi) pathways by generating small RNAs (sRNAs). Here we report the solution structure of the C-terminal domain of Schizosaccharomyces pombe Dicer (Dcr1). The structure reveals an unusual double-stranded RNA binding domain (dsRBD) fold embedding a novel z...
ORGANISM(S): Schizosaccharomyces pombe 
2011-09-22 | E-GEOD-30549 | biostudies-arrayexpress
TranscriptomicsDicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness [RNA_correlations]
Epigenetic mechanisms can be influenced by environmental cues and thus evoke phenotypic variation. This plasticity can be advantageous for adaption, but also detrimental if not under tight control. Although having attracted considerable interest, it remains largely unknown if and how environmental c...
ORGANISM(S): Schizosaccharomyces pombe 
2015-04-23 | E-GEOD-60638 | biostudies-arrayexpress
TranscriptomicsDicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness [RNA_profiles]
Epigenetic mechanisms can be influenced by environmental cues and thus evoke phenotypic variation. This plasticity can be advantageous for adaption, but also detrimental if not under tight control. Although having attracted considerable interest, it remains largely unknown if and how environmental c...
ORGANISM(S): Schizosaccharomyces pombe 
2015-04-23 | E-GEOD-60429 | biostudies-arrayexpress
TranscriptomicsSmall RNA expression in swi6 mutants or dcr1 delta fission yeast Schizosaccharomyces pombe
Small RNA expression in swi6 mutants, dcr1 delta, and wild type fission yeast Schizosaccharomcyces pombe wild type, swi6 mutant, and dcr1 delta mutant
ORGANISM(S): Schizosaccharomyces pombe 
2013-07-20 | E-GEOD-42849 | biostudies-arrayexpress
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