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ProteomicsProteomic profiling of postmortem prefrontal cortex tissue of suicide completers
A total of 36 postmortem brain samples (23 suicide completers, 13 control sudden death) were collected. We evaluated the proteome profile in the prefrontal cortex (Brodmann area 9, 10) with TMT-based quantification using LC-MS/MS. Several bioinformatics tools were used to elucidate biological mechan...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD029845 | Pride
Suicide Proteomics Tandem mass tag Postmortem brain Lc-ms/ms 
ProteomicsQuantitative proteomic analysis identifies TUBB2A as a novel protein biomarker for prediction of distant metastatic breast cancer
Metastasis of breast cancer to other distant organs is fatal to patients. However, few studies have revealed biomarkers associated with distant metastatic breast cancer. Furthermore, the inability of current biomarkers such as HER2, ER and PR, in accurately differentiating between distant metastatic...
ORGANISM(S): Homo sapiens (Human) 
2020-06-05 | PXD016061 | Pride
Formalin-fixed paraffin-embedded (ffpe) tissue Distant metastatic breast cancer Tandem mass tag (tmt) Quantitative proteomics Biomarkers 
ProteomicsEvaluation of nondepleted plasma multiprotein-based model for discriminating psychiatric disorders using multiple reaction monitoring-mass spectrometry: Proof of concept study
Psychiatric evaluation relies on subjective symptoms and behavioral observation, which sometimes lead to misdiagnosis. Although there have been efforts to utilize plasma proteins as objective markers, the depletion method is time-consuming. Therefore, this study aimed to enhance previous quantificat...
ORGANISM(S): Homo Sapiens 
PXD046722 | panorama
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