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TranscriptomicsDNA Microarray Analysis Approach for Unraveling the Ischemic Mouse Brain Transcriptome
Brain ischemia, also termed cerebral ischemia, is a condition in which there is insufficient blood flow to the brain to meet metabolic demand, and results in brain tissue death (cerebral infarction) due to poor oxygen supply (cerebral hypoxia). Our group is interested in the protective effects of ne...
ORGANISM(S): Mus musculus 
2012-03-31 | E-GEOD-28201 | biostudies-arrayexpress
TranscriptomicsAlteration of gene expression patterns in the liver and spleen following exposure to nucleoprotein diet in the mouse LPS injection model
A diet rich in nucleic acids and protamin protein, termed as nucleoprotein (NP), has been attracting a great deal of attention in food science for its beneficial effects. In the present study, we performed a global gene expression profiling in mice fed with NP diet rich in nucleoproteins from the sa...
ORGANISM(S): Mus musculus 
2011-04-01 | E-GEOD-28176 | biostudies-arrayexpress
TranscriptomicsComparative global gene expression profiling of mice liver and spleen fed with nucleoprotein (NP) diets
A diet rich in nucleic acids and protamin protein, termed as nucleoprotein was used for the study. Mice were fed with NP diets for 4 weeks followed by removal of the liver and spleen. Total RNA extracted from livers and spleens was pooled in each group (low NP or LNP-control, and 1.2% NP-treatment, ...
ORGANISM(S): Mus musculus 
2011-04-13 | E-GEOD-28505 | biostudies-arrayexpress
TranscriptomicsUnraveling the Specific Ischemic Core and Penumbra Transcriptome in Permanent Middle Cerebral Artery Occlusion Model Mice Brain Treated with Neuropeptide PACAP38
Our group has been systematically investigating effects of the neuropeptide pituitary adenylate-cyclase activating polypeptide (PACAP) on the ischemic brain. To do so, we have established and utilizing the permanent middle cerebral artery occlusion (PMCAO) mouse model, where PACAP38 (1 pmol) injecti...
ORGANISM(S): Mus musculus 
2014-10-31 | E-GEOD-62884 | biostudies-arrayexpress
TranscriptomicsA DNA Microarray Analysis of Rat Intestine, Spleen and Liver Transcriptome after Oral Administration of Lavender Oil
Lavender oil (LO) – a commonly used oil in aromatherapy with well defined volatile components linalool and linalyl acetate – use in non-traditional medicine is increasing globally. To understand and provide evidence for the potential positive effects of LO on the body, we have established an animal ...
ORGANISM(S): Rattus norvegicus 
2014-11-26 | E-GEOD-63640 | biostudies-arrayexpress
TranscriptomicsUnraveling the Rat Blood Genome-Wide Transcriptome after the Oral Administration of Lavender Oil by a Two-Color Dye-Swap DNA Microarray Approach
Lavender oil (LO) is commonly used oil in aromatherapy, with well-defined volatile components linalool and linalyl acetate, in non-traditional medicine. To understand and demonstrate the potential positive effects of LO on the body, we have established an animal model for investigating the orally ad...
ORGANISM(S): Rattus norvegicus 
2015-04-02 | E-GEOD-67499 | biostudies-arrayexpress
TranscriptomicsWhale (Koiwashi kujira, Minke whale) Meat Extract Supplementation in Diet of Senescence-Accelerated Prone Mouse (SAMP8) Positively Affects Learning Memory Formation and Genome-Wide Changes in the Brain
The present study examines the effects of whale meat extract (WME) supplementation on the senescence-accelerated mouse prone 8 (SAMP8) model at the level of learning memory formation and gene expression profiles genome-wide. Our present study builds up on these previous studies by focusing on two se...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-76459 | biostudies-arrayexpress
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