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GenomicsGenome-wide Ultrabithorax binding analysis reveals highly targeted genomic loci at developmental regulators and a potential connection to Polycomb-mediated regulation
Hox homeodomain transcription factors are key regulators of animal development. They specify the identity of segments along the anterior-posterior body axis in metazoans by controlling the expression of diverse downstream targets, including transcription factors and signaling pathway components. The...
ORGANISM(S): Drosophila melanogaster 
2016-07-03 | E-GEOD-64284 | biostudies-arrayexpress
TranscriptomicsHormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin
Steroid hormones act as important developmental switches and their nuclear receptors regulate many genes. However, few hormone-dependent enhancers have been characterized and important aspects of their sequence architecture, cell type-specific activating and repressing functions, or the regulatory r...
ORGANISM(S): Drosophila melanogaster 
2014-03-27 | E-GEOD-47691 | biostudies-arrayexpress
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