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MetabolomicsFinger sweat analysis enables short interval metabolic biomonitoring in humans

Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues and are impractical for performing time-course studies. The analysis of ...

2021-08-13 | MTBLS2776 | MetaboLights
MetabolomicsFinger sweat analysis enables short interval metabolic biomonitoring in humans

Metabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues and are impractical for performing time-course studies. The analysis of ...

2021-08-13 | MTBLS2772 | MetaboLights
TranscriptomicsExpression data from F344N rats in long and short photoperiods
Rats were housed in either long day (LD, 16:8 hours, light:dark) or short day (SD, 8:16 hours, light dark) photoperiods for 3, 14 and 28 days and brains removed, frozen on dry ice and then hypothalamic arcuate nucleus tissue blocks cut for RNA extraction. At each time point 4 rats were used in each ...
ORGANISM(S): Rattus norvegicus 
2012-02-21 | E-GEOD-27926 | biostudies-arrayexpress
TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
TranscriptomicsFasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
Short-term starvation (STS or fasting) provides protection to normal cells, mice, and possibly patients from a variety of chemotherapy drugs, but the possibility that it may also protect tumor cells renders its translational potential uncertain. Here we show that fasting cycles can be as effective a...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-28556 | biostudies-arrayexpress
UnknownShort-term emotional impact of COVID-19 pandemic on Spaniard health workers.
Not available
S-EPMC7834676 | biostudies-literature
TranscriptomicsExpression data from human hematopoietic stem and progenitor compartments from patients with acute myeloid leukemia with monosomy 7 and healthy controls
We applied a novel approach of parallel transcriptional analysis of multiple, highly fractionated stem and progenitor populations in a genetically defined subset of AML (AML with monosomy 7). We isolated phenotypic long-term HSC (LT-HSC), short-term HSC (ST-HSC), and committed granulocyte-monocyte p...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-35010 | biostudies-arrayexpress
ProteomicsShort and mid term heat stress proteomics characterization in pinus radiata
In order to study in detail short and mid term heat stress molecular response we performed a shotgun proteomics study. One-year-old P. radiata seedlings (plant size ∼33 ± 4 cm) were kept in 1 dm3 pots under a photoperiod of 16 h (400 µmol m−2 s−1) at 25 °C and 50% relative humidity (RH), and 15 °C a...
ORGANISM(S): Pinus radiata (Monterey pine) 
2023-03-11 | PXD032754 | Pride
Pine Orbitrap Climate change 
TranscriptomicsIdentification of differentially regulated genes upon shRNA-mediated knock-down of HLX in the URE leukemia cell line
To study the role of Hlx in hematopoietic differentiation and tumorigenesis, URE cells were infected with short-hairpin-containing pSIH1-H1-copGFP lentiviral vector (System Biosciences, Mountain View, CA) containing either nucleotide sequences targeting luciferase (shControl) or HLX (shHLX). After 2...
ORGANISM(S): Mus musculus 
2012-09-14 | E-GEOD-27939 | biostudies-arrayexpress
TranscriptomicsAnalysis of DNA methylation changes in normal human hematopoietic stem and progenitor cells
DNA methylation analysis on purified human long-term and short-term hematopoietic stem cells (LT-HSC, ST-HSC), common myeloid and megakaryocyte-erythrocyte progenitor cells (CMP, MEP) using HELP arrays. FACS-purified hematopoietic stem and progenitor cell (HSPC) subsets were analyzed for changes in ...
ORGANISM(S): Homo sapiens 
2014-02-07 | E-GEOD-52151 | biostudies-arrayexpress
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