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UnknownMapping of Two Major QTLs Controlling Flowering Time in Brassica napus Using a High-Density Genetic Map.
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S-EPMC9571212 | biostudies-literature
TranscriptomicsComparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza Sativa L.)
Arsenic (As) is a carcinogenic metalloid that is a contaminant widely polluting rice paddy soils around the world. In order to gain better insight into molecular mechanism of rice exposed to As(III) stress, we used next-generation sequencing technology to acquire global transcriptome alteration and ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-01-09 | E-GEOD-36696 | biostudies-arrayexpress
TranscriptomicsChip-chip from Hepatocellular carcinoma (HCC) specimens with H3K4me3
Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-52190 | biostudies-arrayexpress
TranscriptomicsChip-chip from HepG2 cells with EZH2, SUZ12 and H3K27me3
Polycomb group (PcG) proteins including EZH2, SUZ12 and so on, which specifically catalyze trimethylation of histone 3 lysine 27 (H3K27me3), and methylated H3K27 can be recognized by other specific binding proteins to compress chromatin structure, leading to the transcriptional repression of the tar...
ORGANISM(S): Homo sapiens 
2013-11-13 | E-GEOD-52300 | biostudies-arrayexpress
TranscriptomicsChip-chip from Hepatocellular carcinoma (HCC) specimens with H3K27me3
Epigenetic changes commonly occur in hepatocellular carcinoma (HCC) and are associated with aberrant gene expression. Recently, we demonstrated the pivotal role of abnormal H3K4me3 methylation, which is catalyzed by the menin/MLL, a TrxG family, in HCC development. Meanwhile, there is clear evidence...
ORGANISM(S): Homo sapiens 
2013-11-13 | E-GEOD-52301 | biostudies-arrayexpress
TranscriptomicsA cDNA microarray analysis was performed on shRNA KDs of EZH2, SUZ12, BMI1, or CBX8 HepG2 cells.
Polycomb group (PcG) proteins including EZH2, SUZ12 ,BMI1,CBX8 and so on, which specifically catalyze trimethylation of histone 3 lysine 27 (H3K27me3), and methylated H3K27 can be recognized by other specific binding proteins to compress chromatin structure, leading to the transcriptional repression...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-54108 | biostudies-arrayexpress
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
TranscriptomicsTranscription profiling of human hematopoietic stem cells engrafted into fetal goats
Robust human-goat chimerism was achieved by transplanting human CD34+Lin- cord blood cells into fetal goats. We observed a broad distribution of GFP-marked human cells in non-hematopoietic organs including kidney, muscle, lung, and heart of transplant goats. Various marker techniques indicated that...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1801 | biostudies-arrayexpress
TranscriptomicsComparative expression profiling of miRNA during anther development in genetic male sterile and wild type cotton [degradome]
In this study, in order to identify miRNA targets, a degradome library derived from anthers of the WT and GMS (Genetic Male Sterility) mutant representing three stages of development was constructed and sequenced, resulting in the generation of 24.6 million raw reads. After removal of low quality se...
ORGANISM(S): Gossypium hirsutum 
2013-07-28 | E-GEOD-43389 | biostudies-arrayexpress
TranscriptomicsGene Expression Changes in the Development of the Soybean Seed-Cotyledon Stage
We investigated soybean seed development because (1) soybean seeds are a major source of food and fuel, (2) soybean seeds have been an excellent system for studying the basic processes controlling seed development for over three decades, and (3) new soybean genomic resources, including the sequence ...
ORGANISM(S): Glycine max 
2014-05-14 | E-GEOD-57606 | biostudies-arrayexpress
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