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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
MetabolomicsSponge exhalent seawater contains a unique chemical profile of dissolved organic matter
Sponges are efficient filter feeders, removing significant portions of particulate and dissolved organic matter (POM, DOM) from the water column. While the assimilation and respiration of POM and DOM by sponges and their abundant microbial symbiont communities have received much attention, there is ...
2016-02-01 | MTBLS281 | MetaboLights
MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
MetabolomicsMultiyear dynamics of recent and legacy contaminants in a German hill-slope catchment (MS1 data)

Anthropogenic activities cause the release of vast amounts of contaminants into the environment and thus also into surface- and groundwaters. Regulatory monitoring determines whether critical threshold concentrations are surpassed, by mostly occasional probing. This irregular testing, however, do...

2024-06-04 | MTBLS8433 | MetaboLights
MetabolomicsMultiyear dynamics of recent and legacy contaminants in a German hill-slope catchment (MS2 data)

Anthropogenic activities cause the release of vast amounts of contaminants into the environment and thus also into surface- and groundwaters. Regulatory monitoring determines whether critical threshold concentrations are surpassed, by mostly occasional probing. This irregular testing, however, do...

2024-06-04 | MTBLS3533 | MetaboLights
MetabolomicsA Phosphate starvation response gene (psr1-like) is present in Micromonas pusilla and other marine algae and coordinates the metabolic response to phosphate deficiency
Both marine phytoplankton and terrestrial plants have to deal with limited bioavailability of the key life nutrient, phosphate. In freshwater algae and plants, a phosphate starvation response gene (psr1) has been characterized, which encodes for a transcription factor that regulates the metabolic re...
2016-02-01 | MTBLS295 | MetaboLights
UnknownAcute diabetes complications across transition from pediatric to adult care in Ontario and Newfoundland and Labrador: a population-based cohort study.
Not available
S-EPMC7012632 | biostudies-literature
UnknownResources and population served: a description of the Ontario Paediatric Diabetes Network.
Not available
S-EPMC4933641 | biostudies-literature
UnknownSign-specific stimulation 'hot' and 'cold' spots in Parkinson's disease validated with machine learning.
Not available
S-EPMC8042250 | biostudies-literature
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