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GenomicsGenome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4
IRF5 and STAT4 are strongly associated with human systemic lupus erythematosus (SLE). By performing chromatin immunoprecipitation-sequencing (ChIP-Seq) in human peripheral blood mononuclear cells (PBMCs), we identified more than 7000 target genes for IRF5 and STAT4 in stimulated PBMCs. Contrarily, w...
ORGANISM(S): Homo sapiens 
2012-06-08 | E-GEOD-38567 | biostudies-arrayexpress
TranscriptomicsDNA copy number profiling of canine osteosarcoma
Identification of DNA copy number imbalances in 22 spontaneous canine osteosarcoma cases using array comparative genomic hybridization (aCGH) analysis
ORGANISM(S): Canis familiaris 
2013-11-01 | E-MTAB-1986 | biostudies-arrayexpress
GenomicsKarlsson_et_al_OSA
This experiment was conducted to generate targeted resequencing data covering a region associated with osteosarcoma in greyhounds. 8 greyhounds diagnosed with osteosarcoma and 7 greyhounds without tumors were sequenced. DNA from the 15 dogs was used to prepare libraries and hybrid capture performed ...
ORGANISM(S): Canis familiaris 
2013-11-16 | E-MTAB-1984 | biostudies-arrayexpress
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