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ProteomicsNeisseria gonorrhoeae MlaA inversely influences gonococcal virulence and membrane vesicle production
The six-component maintenance of lipid asymmetry (Mla) system is responsible for retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell envelope. Located within the outer membrane MlaA (VacJ) likely acts as a channel to shuttle phospholipids from the outer lea...
ORGANISM(S): Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) 
2019-03-13 | PXD008673 | Pride
Membrane vesicles Neisseria gonorrhoeae Mlaa 
ProteomicsQuantitative proteomics of the Neisseria gonorrhoeae cell envelope and membrane vesicles
Neisseria gonorrhoeae (GC) is a human-specific pathogen, and the agent of a sexually transmitted disease, gonorrhea. There is a critical need for new approaches to study and treat GC infections because of the growing threat of multidrug-resistant isolates and the lack of a vaccine. Despite the impli...
ORGANISM(S): Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) 
2014-12-19 | PXD000549 | Pride
Itraq Neisseria gonorrhoeae Cell envelope Native membrane vesicles Drug and vaccine targets 
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