Sort   by:  
 Page size 
Systematic identification of silencers in human cells
Information Content Differentiates Enhancers From Silencers in Mouse Photoreceptors
Silencers, the yin to enhancers' yang, play a pivotal role in fine-tuning gene expression throughout the genome. However, despite their recognized importance, comprehensive identification of these regulatory elements in the genome is still in its early stages. We developed a method called Ss-STARR-s...
ORGANISM(S): Mus musculus 
2024-12-06 | GSE283488 | GEO
Histone H4 lysine 20 monomethylation is not a mark of transcriptional silencers
To investigate possible smRNAs linked to TMM silencing by single-stranded and double-stranded silencers, we determined sequences of smRNAs by the Illumina high-throughput sequencing platform and compared silencing efficiency of different strategies. We found that single-stranded silencer alone could...
ORGANISM(S): Arabidopsis thaliana 
Transcriptional silencers in Drosophila serve a dual role as transcriptional enhancers in alternate cellular contexts [HiChIP]
Sort   by:  
 Page size