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MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
MetabolomicsKynurenic acid underlies sex-specific immune responses to COVID-19
Sex-related differences in Coronavirus Disease (COVID-19) severity and mortality exist, with the male sex being a potential risk factor1. It was recently shown that patients with mild to moderate SARS-CoV-2 infection have elevated levels of inflammatory cytokines and chemokines, and sex-differences ...
2020-09-08 | MTBLS1987 | MetaboLights
UnknownMinimally invasive ultrasound-guided thread carpal tunnel release: a video demonstration protocol.
Not available
S-EPMC12675869 | biostudies-literature
UnknownBetween China and South Asia: A Middle Asian corridor of crop dispersal and agricultural innovation in the Bronze Age.
Not available
S-EPMC5125436 | biostudies-literature
UnknownFlexibilization of Science, Cognitive Biases, and the COVID-19 Pandemic.
Not available
S-EPMC7449982 | biostudies-literature
UnknownProspection of Fungal Lignocellulolytic Enzymes Produced from Jatoba (Hymenaea courbaril) and Tamarind (Tamarindus indica) Seeds: Scaling for Bioreactor and Saccharification Profile of Sugarcane Bagasse.
Not available
S-EPMC8000596 | biostudies-literature
UnknownPhoto-Selective Nets and Pest Control: Searching Behavior of the Codling Moth Parasitoid Mastrus ridens (Hymenoptera: Ichneumonidae) under Varying Light Quantity and Quality Conditions.
Not available
S-EPMC8305221 | biostudies-literature
TranscriptomicsRNA-seq of whole blood samples from patients with visceral leishmaniasis.
To ascertain which molecular pathways underlying the pathogenesis of human visceral leishmaniasis (VL) caused by the protozoan parasite Leishmania infantum, we performed modular co-expression gene networks analysis using CEMiTool R package and the transcriptional profile of whole blood samples from ...
ORGANISM(S): Homo sapiens 
2018-01-25 | E-MTAB-6137 | biostudies-arrayexpress
UnknownUnveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase.
Not available
S-EPMC9334217 | biostudies-literature
TranscriptomicsStrand-oriented RNAseq of LNCaP prostate cancer cells in culture for 48 h in the absence of androgen
The goal of this study was to use NGS RNAseq deep-sequencing in order to characterize the complement of polyadenylated mRNAs and lncRNAs expressed in LNCaP, a prostate cancer cell line. RNA-seq data were processed as aggregates of the two biological replicates to increase resulting transcriptome cov...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-79301 | biostudies-arrayexpress
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