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UnknownThe role of the transcription factor SIM2 in prostate cancer.
Not available
S-EPMC3235151 | biostudies-literature
GenomicsHSA21 Single-minded 2 (Sim2) binding sites co-localize with super-enhancers and pioneer transcription factors in pluripotent mouse ES cells [ChIP-Seq]
Down syndrome (DS) results from trisomy of chromosome 21 (HSA21). Some DS phenotypes may be directly or indirectly related to the increased expression of specific HSA21 genes, in particular those encoding transcription factors. The HSA21 encoded Single-minded 2 (SIM2) transcription factor has key ne...
ORGANISM(S): Mus musculus 
2015-06-01 | GSE59378 | GEO
TranscriptomicsHSA21 Single-minded 2 (Sim2) binding sites co-localize with super-enhancers and pioneer transcription factors in pluripotent mouse ES cells [RNA-Seq]
Down syndrome (DS) results from trisomy of chromosome 21 (HSA21). Some DS phenotypes may be directly or indirectly related to the increased expression of specific HSA21 genes, in particular those encoding transcription factors. The HSA21 encoded Single-minded 2 (SIM2) transcription factor has key ne...
ORGANISM(S): Mus musculus 
2015-06-01 | GSE59373 | GEO
UnknownCharacterization of functionally deficient SIM2 variants found in patients with neurological phenotypes.
Not available
S-EPMC9342896 | biostudies-literature
UnknownSIM2, associated with clinicopathologic features, promotes the malignant biological behaviors of endometrial carcinoma cells.
Not available
S-EPMC11987308 | biostudies-literature
UnknownPotential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies.
Not available
S-EPMC3563522 | biostudies-literature
UnknownHSA21 Single-Minded 2 (Sim2) Binding Sites Co-Localize with Super-Enhancers and Pioneer Transcription Factors in Pluripotent Mouse ES Cells.
Not available
S-EPMC4425456 | biostudies-literature
UnknownThe bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence.
Not available
S-EPMC2441813 | biostudies-literature
UnknownCloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.
Not available
S-EPMC310662 | biostudies-literature
UnknownExploratory investigation on functional significance of ETS2 and SIM2 genes in Down syndrome.
Not available
S-EPMC3826905 | biostudies-literature
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