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TranscriptomicsGene expression analysis in control and HIF-2 alpha deficient murine lung endothelial cells under hypoxia
Journal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13. Title : Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Authors : Skuli N, Liu L, Runge A, Wang T, Yuan L, Patel S, Iruela-Arispe L, Simon MC, Keith B. Abstract : Hyp...
ORGANISM(S): Mus musculus 
2009-07-15 | E-GEOD-16067 | biostudies-arrayexpress
TranscriptomicsIdentification of candidate genes affecting juvenile wood stiffness in Pinus radiata
Wood stiffness is the most important wood quality trait of forest trees for structural timber production. We investigated genes differentially transcribed in radiate pine trees with distinct wood stiffness using bulked segregant analysis (BSA) and cDNA microarrays. Transcript accumulation in earlywo...
ORGANISM(S): Pinus radiata 
2011-06-01 | E-GEOD-23020 | biostudies-arrayexpress
TranscriptomicsPBMC IFNg Dose Reponse
PBMC response to three concentrations of IFNg (0.006, 0.6 and 60 pM) from 0-12h. Abstract: Background Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and ind...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-16252 | biostudies-arrayexpress
TranscriptomicsForkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae [Sequence Data]
The replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function. The characteristic initiation timing of specific origins is thought to reflect their chromatin environment or sub-nuclear positioning, how...
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-20 | E-GEOD-33677 | biostudies-arrayexpress
TranscriptomicsPBMC Cell Subset Stimulation
PBMC cell subsets were treated with 0.6 pM IFNg for 0-24h and compared to mock-treated time series. Abstract: Background Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the produc...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-16253 | biostudies-arrayexpress
TranscriptomicsRibo-seq analysis of Saccharomyces cerevisiae with and without 10 minute glucose starvation
Ribosome profiling (Ribo-Seq) and RNA-Seq analysis of Saccharomyces cerevisiae with and without 10 minute glucose starvation to determine effects on translation.
ORGANISM(S): Saccharomyces cerevisiae 
2021-09-30 | E-MTAB-9094 | biostudies-arrayexpress
TranscriptomicsPBMC Cytokine Comparison
Treatment of PBMC with 0.6 pM cytokine from 0-24h Abstract: Background Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, homotypic and he...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-16251 | biostudies-arrayexpress
TranscriptomicsDSIF and RNA polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes
Histone deacetylase Rpd3 is part of two distinct complexes: the large (Rpd3L) and small (Rpd3S) complexes. While Rpd3L targets specific promoters for gene repression, Rpd3S is recruited to ORFs to deacetylate histones in the wake of RNA polymerase II, to prevent cryptic initiation within genes. Meth...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-28 | E-GEOD-22636 | biostudies-arrayexpress
TranscriptomicsAnalysis of RIP-seq of Ded1 and eIF4A(Tif1) with and without glucose depletion
The aim of this experiment was to look at RNAs which associate with DEAD-box RNA helicases with and without 10 minutes of glucose starvation.
ORGANISM(S): Saccharomyces cerevisiae 
2021-09-30 | E-MTAB-9095 | biostudies-arrayexpress
TranscriptomicsAnalysis of P-body (Dcp1) and Stress Granule (Pbp1) RNA content
Non-membrane-bound compartments such as mRNA processing bodies (PBs) and stress granules (SGs) play important roles in the regulation of gene expression following environmental stresses. Here we perform RIP-seq to determine the RNA interactors of Dcp1 (PB marker) and Pbp1 (SG marker) before and afte...
ORGANISM(S): Saccharomyces cerevisiae 
2021-09-30 | E-MTAB-9096 | biostudies-arrayexpress
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