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TranscriptomicsHuman Bone Marrow Stromal Cells cultured on polymer scaffolds with varied properties
Microarray analysis was used to evaluate expression differences from a single donor human bone marrow stromal cells (hBMSCs) as a function of varied polymer-based tissue engineering scaffolds. The results revealed that gene expression patterns of hBMSCs grouped according to scaffold. A library of sc...
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-50743 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of HCT-116 versus HCT-116 treated with 5-aza-2'-deoxycytidine processing human colon cancer cell lines
UCRs expression signature of HCT-116 cell lines versus HCT-116 cell line treated with DNA methylation inhibitor 5-aza-2'-deoxycytidine
ORGANISM(S): Homo sapiens 
2010-03-09 | E-MTAB-196 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in control and BRG1-knockdown H358 cell lines
Transcription was assessed in the human H358 NSCLC cell line after knockdown of BRG1, one of the mutually exclusive subunits of the SWI/SNF chromatin remodeling complex, by 2 different shRNAs. One biolgical replicate of each treatment; 4 technical replicates of each treatment.
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58542 | biostudies-arrayexpress
TranscriptomicsMYC activation and BCL2L11 silencing by a tumor virus through the large-scale reconfiguration of enhancer-promoter hubs [EREB]
Lymphomagenesis in the presence of deregulated MYC expression requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus (EBV) activate MYC and silence BCL2L11...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-82149 | biostudies-arrayexpress
GenomicsThe yeast GG-NER complex evicts histone H2A.Z-containing barrier nucleosomes from CID boundaries during DNA repair
Background: Repair of DNA damage requires chromatin remodeling to permit removal of the lesions. How nucleosomes are remodelled to initiate repair of DNA damage remains largely unknown. Here, we describe how chromatin is altered during repair of UV-induced DNA damage at the level of the linear organ...
ORGANISM(S): Saccharomyces cerevisiae 
2018-12-06 | E-MTAB-6569 | biostudies-arrayexpress
TranscriptomicsMYC activation and BCL2L11 silencing by a tumor virus through the large-scale reconfiguration of enhancer-promoter hubs [Bcell]
Lymphomagenesis in the presence of deregulated MYC expression requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus (EBV) activate MYC and silence BCL2L11...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-82148 | biostudies-arrayexpress
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