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MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicsMicroarray analysis of transcripts in the liver of gilthead sea bream with high plasma cortisol levels induced by slow-release cortisol implants
The present work was designed to assess the effects of high plasma cortisol levels induced by slow-release cortisol implants in the mRNA transcription of the GR in the different organs of the Sparus aurata, including liver. For that purpose fish were intraperitoneally injected with the implants cont...
ORGANISM(S): Sparus aurata 
2011-07-19 | E-GEOD-30782 | biostudies-arrayexpress
ProteomicsInheritance of old mitochondria controls early CD8+ T cell fate commitment and is regulated by autophagy - Pride 2
T cell immunity is impaired during ageing, particularly in memory responses needed for efficient vaccination. Autophagy and asymmetric cell division (ACD) are cell biological mechanisms key to memory formation, which undergo a decline upon ageing. However, despite the fundamental importance of these...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-21 | PXD053316 | Pride
Mitochondria Cd* t cells 
GenomicsSMAD2/3 chromatin immunoprecipitation sequencing (ChIP-seq) in human naïve and primed human pluripotent stem cells
The aim of this experiment was to investigate the role of TGFβ signalling pathway in human pluripotency, through ChIP-seq analysis of its main downstream effector SMAD2/3 in naïve and primed human pluripotent stem cells (hPSCs).
ORGANISM(S): Homo sapiens 
2021-08-13 | E-MTAB-10017 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of primary visceral adipocytes isolated from wildtype mice or mice with adipocyte specific deletion of Atg7
Genes involved in the autophagic pathway are risk factors for the development of inflammatory bowel disease. In addition, patients with Crohn’s disease exhibit a profound expansion of mesenteric fat during the pathology. We investigated in our study the role of autophagy in mature adipocyte during i...
ORGANISM(S): Mus musculus 
2023-01-14 | E-MTAB-12498 | biostudies-arrayexpress
UnknownCell division protein FtsK coordinates bacterial chromosome segregation and daughter cell separation in Staphylococcus aureus
Not available
S-SCDT-10_15252-EMBJ_2022112140 | biostudies-other
ProteomicsOstreococcus OlV1/OlV7 lysate DOM
Dissolved organic matter extracts prepared by viral lysates of Ostreococcus lucimarinus CCMP2972, infected by lytic viruses OlV1 and OlV7, as well as uninfected controls, under standard-light (~110uE/m2s; "SL") and low-light (15uE/m2s, "LL") irradiance.
ORGANISM(S): Ostreococcus Lucimarinus Cce9901 (ncbitaxon:436017) Ostreoccus Lucimarinus Virus Olv7 Ostreococcus Lucimarinus Virus 1 (ncbitaxon:880162) 
2019-02-12 | MSV000083434 | MassIVE
UnknownRepurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.
Not available
S-EPMC7727327 | biostudies-literature
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