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TranscriptomicsSHAE004: SARS-CoV, SARS-dORF6 and SARS-BatSRBD infection of HAE cultures.
HAE cultures were infected with SARS-CoV, SARS-dORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. Time Points = 0, 12, 24, 36, 48, 60, 72, 84 and 96 hrs post-infection for SARS-...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-47962 | biostudies-arrayexpress
TranscriptomicsSCL006,icSARS CoV Urbani or icSARS Bat SRBD (spike receptor binding domain from the wild type strain Urbani to allow for infection of human and non-human primate cells) infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the cSARS Bat SRBD strain at MOI of 1.0. Cells samples were collected at 0, 7, 1...
ORGANISM(S): Homo sapiens 
2012-05-06 | E-GEOD-37827 | biostudies-arrayexpress
TranscriptomicsSCL005: icSARS CoV Urbani or icSARS deltaORF6 infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV or the icSARS deltaORF6 mutant. Calu-3 cells were infected with either icSARS CoV or the icSARS deltaORF6 mutant at MOI of 5.0. Cells samples were collected at 0, 3,...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-33267 | biostudies-arrayexpress
TranscriptomicsPrimary human microvascular endothelial cell transcriptome (mRNA) response to a wild type Mers-CoV (icMERS-CoV EMC2012)
The purpose is to obtain samples for mRNA analysis in primary human microvascular endothelial cells infected with wild type Mers-CoV (icMERS). Human microvascular endothelial cells were infected with a multiplicity of infection of 5 PFU per cell. Infected samples were collected in quintuplet; time-...
ORGANISM(S): Homo sapiens 
2016-03-25 | E-GEOD-79218 | biostudies-arrayexpress
TranscriptomicsPrimary human dendritic cell transcriptome response to a wild type Mers-CoV (icMERS)
The purpose is to obtain samples for mRNA analysis in primary human dendritic cells infected with wild type Mers-CoV (icMERS). Human primary dendritic cells were infected with a multiplicity of infection of 5 PFU per cell. Infected samples were collected in triplet; time-matched mocks were collecte...
ORGANISM(S): Homo sapiens 
2016-03-15 | E-GEOD-79172 | biostudies-arrayexpress
TranscriptomicsHuman Calu-3 cell transcriptome response to a wild type infectious clone of Middle Eastern Respiratory Syndrome (icMERS) coronavirus and icMERS mutant viruses
The purpose of this experiment was to obtain samples for transcriptome analysis using wild type infectious clone of Middle Eastern Respiratory Syndrome (icMERS) coronavirus and icMERS mutant viruses: icMERS-RFP, icMERS-dNSP16, icMERS-d4B, and icMERS-d3-5. For protocol details, please search for the...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-65574 | biostudies-arrayexpress
TranscriptomicsPrimary human microvascular endothelial cell transcriptome (microRNA) response to wild type Mers-CoV (icMERS-CoV EMC2012)
The purpose is to obtain samples for microRNA analysis in primary human microvascular endothelial cells infected with wild type Mers-CoV (icMERS). Human microvascular endothelial cells were infected with a multiplicity of infection of 5 PFU per cell. Infected samples were collected in quintuplet; t...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-79216 | biostudies-arrayexpress
TranscriptomicsSHAE002: SARS-CoV, SARS-dORF6 and SARS-BatSRBD infection of HAE cultures.
HAE cultures were infected with SARS-CoV, SARS-dORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. Time Points = 0, 12, 24, 36, 48, 60, 72, 84 and 96 hrs post-infection for SARS-...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-47960 | biostudies-arrayexpress
TranscriptomicsSHAE003: SARS-CoV, SARS-dORF6 and SARS-BatSRBD infection of HAE cultures.
HAE cultures were infected with SARS-CoV, SARS-ddORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. Time Points = 0, 12, 24, 36, 48, 60, 72, 84 and 96 hrs post-infection for SARS...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-47961 | biostudies-arrayexpress
TranscriptomicsSCL008: icSARS CoV, icSARS-deltaNSP16 or icSARS ExoNI infections of the 2B4 clonal derivative of Calu-3 cells - Time course
Purpose of experiment was to compare transcriptomics of 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV, icSARS-deltaNSP16 or icSARS ExoNI mutants. 2B-4 cells (clonal derivatives of Calu-3 cells) were infected with either icSARS CoV, icSARS deltaNSP16 or icSARS ExoNI. ...
ORGANISM(S): Homo sapiens 
2014-05-23 | E-GEOD-48142 | biostudies-arrayexpress
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