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TranscriptomicsMesenchymal stromal cells isolated from bronchoalveolar lavage and digest parenchymal lung tissue
Stromal support is critical to the achievement of lung homeostasis and the maintenance of an effective epithelial barrier, and yet previous studies have found a positive association between the number of mesenchymal stromal cell populations (MSCs) isolated from the alveolar space and human diseases ...
ORGANISM(S): Homo sapiens 
2016-07-04 | E-GEOD-74284 | biostudies-arrayexpress
UnknownExtracellular vesicles in COVID-19 convalescence can regulate T cell metabolism and function.
Not available
S-EPMC10371842 | biostudies-literature
UnknownHuman Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy.
Not available
S-EPMC5407052 | biostudies-literature
TranscriptomicsPurification and transcriptomic analysis of mouse fetal Leydig cells reveals candidate genes for disorders of sex development
To examine the transcriptome of early testicular somatic cells during gonadogenesis at 12.5dpc RNA sequencing (RNA-Seq) was performed on murine primary testicular cell lineages isolated from the Sf1-eGFP line by FACS. The three main somatic cell lineages of the testis were isolated: the Sertoli cell...
ORGANISM(S): Mus musculus 
2015-05-21 | E-GEOD-65498 | biostudies-arrayexpress
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
UnknownCopy number architectures define treatment-mediated selection of lethal prostate cancer clones.
Not available
S-EPMC10415299 | biostudies-literature
UnknownHuman Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy.
Not available
S-EPMC7026892 | biostudies-literature
UnknownActivation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
Not available
S-EPMC4231123 | biostudies-literature
TranscriptomicsExpression data from control and Phospholipid dependent kinase 1 (PDK1) null cytotoxic T-lymphocytes (CTL) and from control and Akt inhibitor treated CTL
In cytotoxic T cells (CTL), Protein Kinase B /Akt is activated by the T cell antigen receptor (TCR) and the cytokine Interleukin 2 (IL2), in part by phosophorylation of Akt by Phospholipid dependent kinase 1 (PDK1). The role of PDK1 and Akt in CTL has however not been fully defined. In order to expl...
ORGANISM(S): Mus musculus 
2011-02-01 | E-GEOD-26290 | biostudies-arrayexpress
UnknownManagement change following NGS diagnosis of inborn errors of immunity: The Australasian experience.
Not available
S-EPMC13629484 | biostudies-literature
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