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TranscriptomicsGenome-wide analysis of esopageal adenocarcinoma tumor biopsy using high-density single-nucleotide polymorphism arrays.
We applied whole-genome single nucleotide polymorphism (SNP) arrays to define a comprehensive genetic profile of 23 esophageal adenocarcinoma (EAC) primary tumor biopsies based on loss of heterozygosity (LOH) and DNA copy number changes. Alterations were common, averaging 97 (range 23-208) per tumor...
ORGANISM(S): Homo sapiens 
2008-06-01 | E-GEOD-10506 | biostudies-arrayexpress
TranscriptomicsA statistical method for detecting genomic aberrations in heterogeneous tumour samples from single nucleotide polymorphism genotyping data
SNP array analysis of microdissected tumor vs stroma vs surgically obtained tumor DNA was extracted from total tumor material, from microdissected stroma and microdissected, pure tumor tissue
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-23785 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of Eucalyptus camaldulensis seedlings subjected to water stress reveals functional single nucleotide polymorphisms and genes under selection.
Purpose: Water stress limits plant survival and production in many parts of the world. Identification of genes and alleles responding to water stress conditions is important in breeding plants better adapted to drought. Currently there are no studies examining the transcriptome wide gene and allelic...
ORGANISM(S): Eucalyptus camaldulensis 
2012-07-17 | E-GEOD-39369 | biostudies-arrayexpress
TranscriptomicsGSTM3 single nucleotide polymorphism (rs7483) associated with peripheral BMC expression in Alzheimer disease
Comparisons between the sample groups (normal elderly control (NEC) and Alzheimer disease (AD)) allowed the identification of genes with disease expression patterns associated with the glutathione S-transferase M3 single nucleotide polymorphism rs7483. Keywords: biological repeat Peripheral blood mo...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-4227 | biostudies-arrayexpress
TranscriptomicsGene-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia.
Gene-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia.
ORGANISM(S): Homo sapiens 
2012-06-09 | E-TABM-1165 | biostudies-arrayexpress
TranscriptomicsComparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide SNP array analysis
Stromal contamination is one of the major confounding factors in the analysis of primary solid tumor samples by single nucleotide polymorphism (SNP) arrays. As we propose to employ genome-wide SNP microarray analysis as a diagnostic platform for neuroblastoma, the sensitivity, specificity, and accur...
ORGANISM(S): Homo sapiens 
2009-01-31 | E-GEOD-14656 | biostudies-arrayexpress
TranscriptomicsmicroRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia patients 60 years.\//\<
microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia patients <60 years.
ORGANISM(S): Homo sapiens 
2012-06-09 | E-TABM-1166 | biostudies-arrayexpress
TranscriptomicsMicroRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia patients >=60 years.
MicroRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia patients >=60 years.
ORGANISM(S): Homo sapiens 
2012-06-09 | E-TABM-1167 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human osteosarcom) cell lines expressing wild type hGR or N363SA to establish a link between the N363S glucocorticoid teceptor polymorphism and altered gene expression related to human disease
A single nucleotide polymorphism (SNP) in the human glucocorticoid receptor (GR), N363S, has been the focus of several clinical studies, and some epidemiological data link this SNP to increased glucocorticoid sensitivity, coronary artery disease and increased body mass index (BMI). However, molecul...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-5796 | biostudies-arrayexpress
GenomicsA non-coding single nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation
A non-coding single nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation
PRJNA852543 | ENA
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