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TranscriptomicsP. pacificus and C. elegans exposed to various pathogens
This SuperSeries is composed of the following subset Series: GSE36413 : C. elegans young adults : Exposed to Bacillus thuringiensis DB27 vs. E. coli OP50 exposure; 4hours GSE36493: C. elegans young adults: Exposed to Staphylococcus aureus versus exposed to E. coli OP50 : 4 hours GSE36499: C. elegan...
ORGANISM(S): Pristionchus pacificus 
2012-03-20 | E-GEOD-36636 | biostudies-arrayexpress
TranscriptomicsEffect of germline ablation in the nematode P. pacificus
Transcriptional profiling of germline-ablated P. pacificus worms versus un-ablated wild-type controls. Food source E. coli OP50 for both conditions. The goal was to identify genes that regulate the enhanced longevity observed in germline-deficient animals. One-condition experiments. Germline ablated...
ORGANISM(S): Pristionchus pacificus 
2012-04-17 | E-GEOD-37331 | biostudies-arrayexpress
TranscriptomicsImmune reposne of germline-ablated P. pacificus exposed to S. marcescens
Transcriptional profiling of germline-ablated P. pacificus worms exposed to S. marcescens for 8 hours versus germline-ablated P. pacificus exposed to the control E. coli OP50. First goal was to identify genes that are involved in immune response of germline-ablated P. pacificus when exposed to S. ma...
ORGANISM(S): Pristionchus pacificus 
2012-04-17 | E-GEOD-37337 | biostudies-arrayexpress
TranscriptomicsP. pacificus young adults: Exposed to Xenorhabdus nematophila versus exposed to E. coli OP50 : 4 hours
Transcriptional profiling of P. pacificus young adult worms exposed to pathogen Xenorhabdus nematophila for 4 hours versus age-matched worms exposed to control lab food E. coli OP50. The goal was to identify genes regulated in response to pathogen. The broader goal of study was to study evolution of...
ORGANISM(S): Pristionchus pacificus 
2012-03-21 | E-GEOD-36523 | biostudies-arrayexpress
TranscriptomicsP. pacificus young adults: Exposed to Serratia marcescens versus exposed to E. coli OP50 : 4 hours
Transcriptional profiling of P. pacificus young adult worms exposed to pathogen Serratia marcescens for 4 hours versus age-matched worms exposed to control lab food E. coli OP50. The goal was to identify genes regulated in response to pathogen. The broader goal of study was to study evolution of pat...
ORGANISM(S): Pristionchus pacificus 
2012-03-21 | E-GEOD-36521 | biostudies-arrayexpress
TranscriptomicsP. pacificus young adults: Exposed to Staphylococcus aureus versus exposed to E. coli OP50 : 4 hours
Transcriptional profiling of P. pacificus young adult worms exposed to pathogen Staphylococcus aureus for 4 hours versus age-matched worms exposed to control lab food E. coli OP50. The goal was to identify genes regulated in response to pathogen. The broader goal of study was to study evolution of p...
ORGANISM(S): Pristionchus pacificus 
2012-03-21 | E-GEOD-36519 | biostudies-arrayexpress
TranscriptomicsP. pacificus young adults: Exposed to Bacillus thuringiensis DB27 versus exposed to E. coli OP50 : 4 hours
Transcriptional profiling of P. pacificus young adult worms exposed to pathogen Xenorhabdus nematophila for 4 hours versus age-matched worms exposed to control lab food E. coli OP50. The goal was to identify genes regulated in response to pathogen. The broader goal of study was to study evolution of...
ORGANISM(S): Pristionchus pacificus 
2012-03-21 | E-GEOD-36517 | biostudies-arrayexpress
GenomicsThe RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis
The RelA hydrolase domain acts as a molecular switch for (p)ppGpp synthesis
PRJNA632006 | ENA
TranscriptomicsP. pacificus : Dauers and Dauer-Exit at 12 hour time-point vs. Mix-stage worms
Transcriptional profiling of P. pacificus worms from (1) dauer stage, or (2) dauer-exit at 12 hours stage, compared to mix-stage worms as a common reference. The goal was to determine genes regulated during dauer development and recovery or exit from dauer stage. This data was then compared to data ...
ORGANISM(S): Pristionchus pacificus 
2011-09-02 | E-GEOD-31861 | biostudies-arrayexpress
TranscriptomicsThe epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women
Background Obesity is associated with changes in fat cell gene expression and metabolism. What drives these changes is not well understood. We aimed to explore fat cell epigenetics, i.e., DNA methylation, as one mediator of gene regulation, in obese women. The global DNA methylome for abdominal subc...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-67024 | biostudies-arrayexpress
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